(Q34280196)

1 August 2017

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title

Stress, DNA damage and ageing -- an integrative approach (English)

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1 August 2017

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von Zglinicki T

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1 August 2017

Bürkle A

series ordinal

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1 August 2017

Kirkwood TB

series ordinal

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1 August 2017

publication date

1 July 2001

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1 August 2017

published in

Experimental Gerontology

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

1049-1062

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Selective loss of poly(ADP-ribose) and the 85-kDa fragment of poly(ADP-ribose) polymerase in nucleoli during alkylation-induced apoptosis of HeLa cells

1 August 2017

cites work

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7 January 2021

Telomere states and cell fates

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle

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7 January 2021

Poly(ADP-ribosyl)ation: a posttranslational protein modification linked with genome protection and mammalian longevity

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7 January 2021

Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Telomere length and replicative aging in human vascular tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Oxidative DNA damage and senescence of human diploid fibroblast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Thermolabile 8-hydroxyguanine DNA glycosylase with low activity in senescence-accelerated mice due to a single-base mutation.

1 reference

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7 January 2021

There is substantial agreement among interspecies estimates of DNA repair activity

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Neuropathological and histochemical changes in a multiple mitochondrial DNA deletion disorder

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Cytochrome c oxidase deficient cells accumulate in the hippocampus and choroid plexus with age.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Telomerase expression restores dermal integrity to in vitro-aged fibroblasts in a reconstituted skin model.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

A proposed refinement of the mitochondrial free radical theory of aging

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Inhibition of telomerase limits the growth of human cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

The serial cultivation of human diploid cell strains

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Positive correlation between mammalian life span and cellular resistance to stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

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7 January 2021

Network theory of aging

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https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Is aging as complex as it would appear? New perspectives in aging research

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

A network theory of ageing: the interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the ageing process

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Accumulation of defective mitochondria through delayed degradation of damaged organelles and its possible role in the ageing of post-mitotic and dividing cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

trans-dominant inhibition of poly(ADP-ribosyl)ation sensitizes cells against gamma-irradiation and N-methyl-N'-nitro-N-nitrosoguanidine but does not limit DNA replication of a polyomavirus replicon

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Mammalian mitochondrial genetics: heredity, heteroplasmy and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Cataloging altered gene expression in young and senescent cells using enhanced differential display

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

DNA ends: maintenance of chromosome termini versus repair of double strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Accumulation of short telomeres in human fibroblasts prior to replicative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Negative regulation of alkylation-induced sister-chromatid exchange by poly(ADP-ribose) polymerase-1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

The p66shc adaptor protein controls oxidative stress response and life span in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Poly(ADP-ribose) polymerase: a molecular nick-sensor

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Multiparametric staining to identify apoptotic human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Position effect of human telomeric repeats on replication timing

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

DNA Repair and the Evolution of Longevity: A Critical Analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Microarray analysis of replicative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Accelerated telomere shortening in fibroblasts after extended periods of confluency.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Tankyrase promotes telomere elongation in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Deletion of Ku86 causes early onset of senescence in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Telomeres: beginning to understand the end.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2801%2900111-5

7 January 2021

10.1016/S0531-5565(01)00111-5

Identifiers

DOI

1 reference

release_m7up6o3utvgvzgh6rvksv2ihiy

1 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/m7up6o3utvgvzgh6rvksv2ihiy

24 November 2022

mapped directly with Wikidata item

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