(Q34275992)

1 August 2017

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title

Pathogenesis of rheumatoid arthritis: the role of synoviocytes (English)

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1 August 2017

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Yamanishi Y

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1 August 2017

Firestein GS

series ordinal

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1 August 2017

publication date

1 May 2001

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Rheumatic Diseases Clinics of North America

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

355-371

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Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family

1 August 2017

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Generation and characterization of aggrecanase. A soluble, cartilage-derived aggrecan-degrading activity

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7 January 2021

Function and activation of NF-kappa B in the immune system

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7 January 2021

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

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7 January 2021

Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases

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7 January 2021

The ras gene family and human carcinogenesis

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7 January 2021

Posttranscriptional regulation of collagenase‐1 gene expression in synoviocytes by adenosine receptor stimulation

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7 January 2021

HPRT- mutant T cells in the peripheral blood and synovial tissue of patients with rheumatoid arthritis

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7 January 2021

Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma

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Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

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Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts

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7 January 2021

Constitutive expression of c-fos and c-jun, overexpression of ets-2, and reduced expression of metastasis suppressor gene nm23-H1 in rheumatoid arthritis

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7 January 2021

Pulmonary inflammatory, chemokine, and mutagenic responses in rats after subchronic inhalation of carbon black

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Induction and activation of procollagenase in rabbit synovial fibroblasts after treatment with active oxygen released by xanthine/xanthine oxidase

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

Histomorphological basis of articular cartilage destruction in rheumatoid arthritis

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7 January 2021

A genetic model for colorectal tumorigenesis

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7 January 2021

Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?

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7 January 2021

Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium.

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7 January 2021

Signal transduction and transcription factors in rheumatic disease

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7 January 2021

Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA-DR) in rheumatoid arthritis and osteoarthritis synovium. Quantitative analysis and effect of intraarticular corticosteroids

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7 January 2021

How important are T cells in chronic rheumatoid synovitis?

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7 January 2021

Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent

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7 January 2021

The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives

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7 January 2021

Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent

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7 January 2021

Activation of transcription factor NF-kappa B in human synovial cells in response to tumor necrosis factor alpha

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7 January 2021

In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium

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7 January 2021

AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis

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7 January 2021

Dominant-negative p53 mutations in rheumatoid arthritis

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7 January 2021

Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65

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7 January 2021

Rheumatoid arthritis. Pathophysiology and implications for therapy

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7 January 2021

C-myc antisense oligodeoxynucleotides can induce apoptosis and down-regulate Fas expression in rheumatoid synoviocytes

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7 January 2021

Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop

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7 January 2021

Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro

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7 January 2021

Monoclonal expansion of synoviocytes in rheumatoid arthritis

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7 January 2021

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone

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7 January 2021

Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium

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7 January 2021

The major ras induced protein in NIH3T3 cells is cathepsin L

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7 January 2021

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

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7 January 2021

The Ras signal transduction pathway

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7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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7 January 2021

Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts

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7 January 2021

Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids

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7 January 2021

Cancer. p53, guardian of the genome

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7 January 2021

Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

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7 January 2021

Cell-mediated catabolism of aggrecan. Evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain

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7 January 2021

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

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7 January 2021

Physical and functional interaction between WT1 and p53 proteins

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7 January 2021

Hypoxia, oxidative stress and rheumatoid arthritis

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7 January 2021

Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

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7 January 2021

Expression of the thioredoxin-thioredoxin reductase system in the inflamed joints of patients with rheumatoid arthritis

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7 January 2021

Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

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7 January 2021

Antisense oligonucleotides targeting c-fos mRNA inhibit rheumatoid synovial fibroblast proliferation

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7 January 2021

DNA damage and mutation in human cells exposed to nitric oxide in vitro

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7 January 2021

Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis

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7 January 2021

Role of the proteasome and NF-kappaB in streptococcal cell wall-induced polyarthritis

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7 January 2021

The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining

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7 January 2021

Mutations of the p53 tumour suppressor gene in erosive rheumatoid synovial tissue

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7 January 2021

H-ras oncogene point mutations in arthritic synovium

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7 January 2021

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

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7 January 2021

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

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7 January 2021

Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-beta1 in human prostate cancer cell lines

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7 January 2021

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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7 January 2021

A survey of telomerase activity in human cancer

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Studies on the contribution of c-fos/AP-1 to arthritic joint destruction

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7 January 2021

Apoptosis by p53: mechanisms, regulation, and clinical implications

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7 January 2021

p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression

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7 January 2021

p53 overexpression in synovial tissue from patients with early and longstanding rheumatoid arthritis compared with patients with reactive arthritis and osteoarthritis

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7 January 2021

Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases.

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7 January 2021

Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Cathepsin B in synovial cells at the site of joint destruction in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

The effect of dexamethasone on the expression of activated NF-kappa B in adjuvant arthritis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Basic FGF-induced activation of telomerase in rheumatoid synoviocytes

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Constitutive expression of a 92-kD gelatinase (type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Differential effects of transforming growth factor-beta on the expression of collagenase-1 and collagenase-3 in human fibroblasts

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Possible correction of abnormal rheumatoid arthritis synovial cell function byjun D transfection in vitro

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Roles of aggrecan, a large chondroitin sulfate proteoglycan, in cartilage structure and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

DNA deaminating ability and genotoxicity of nitric oxide and its progenitors

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Transforming growth factor beta stimulates the production of the tissue inhibitor of metalloproteinases (TIMP) by human synovial and skin fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Different mechanisms of synovial hyperplasia in rheumatoid arthritis and pigmented villonodular synovitis: the role of telomerase activity in synovial proliferation

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

Mutagenesis associated with nitric oxide production in macrophages

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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970206-4

7 January 2021

10.1016/S0889-857X(05)70206-4

Identifiers

DOI

1 reference

1 August 2017

1 reference