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Lysophosphatidic acid in atherosclerotic diseases

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Europe PubMed Central

PubMed publication ID

1 August 2017

Lysophosphatidic acid in atherosclerotic diseases (English)

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Europe PubMed Central

PubMed publication ID

1 August 2017

atherosclerosis

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based on heuristic

inferred from title

Andreas Schober

1

object named as

Andreas Schober

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Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Wolfgang Siess

2

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Europe PubMed Central

PubMed publication ID

1 August 2017

language of work or name

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publication date

1 October 2012

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Europe PubMed Central

PubMed publication ID

1 August 2017

British Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

1 August 2017

167

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

465-482

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Quantification of bioactive sphingo- and glycerophospholipid species by electrospray ionization tandem mass spectrometry in blood

1 reference

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6 July 2018

Atherosclerosis: current pathogenesis and therapeutic options

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling

1 reference

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6 July 2018

Inhibition of lipoprotein-associated phospholipase A2 ameliorates inflammation and decreases atherosclerotic plaque formation in ApoE-deficient mice

1 reference

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6 July 2018

Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells

1 reference

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6 July 2018

Non-Edg family LPA receptors: the cutting edge of LPA research

1 reference

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6 July 2018

Progress and challenges in translating the biology of atherosclerosis

1 reference

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6 July 2018

Anti-inflammatory therapeutics for the treatment of atherosclerosis

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6 July 2018

Macrophages in the pathogenesis of atherosclerosis

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Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity

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Recent Insights into the Relationship between Inflammatory Liver Diseases and Atherosclerosis

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6 July 2018

Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid

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6 July 2018

The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation

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6 July 2018

The immune system in atherosclerosis

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6 July 2018

Structural basis of substrate discrimination and integrin binding by autotaxin

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Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

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6 July 2018

Lysophosphatidic Acid Level and the Incidence of Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation

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6 July 2018

GPR92/LPA₅ lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaques

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6 July 2018

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature

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6 July 2018

Phospholipase A2 inhibition and atherosclerotic vascular disease: prospects for targeting secretory and lipoprotein-associated phospholipase A2 enzymes

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6 July 2018

Aiming drug discovery at lysophosphatidic acid targets

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6 July 2018

Regulation of lysophosphatidate signaling by autotaxin and lipid phosphate phosphatases with respect to tumor progression, angiogenesis, metastasis and chemo-resistance

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Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid

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6 July 2018

Autotaxin--an LPA producing enzyme with diverse functions

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6 July 2018

Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

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6 July 2018

Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation

1 reference

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6 July 2018

A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation

1 reference

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6 July 2018

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

1 reference

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6 July 2018

Autotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration.

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6 July 2018

LPA receptors: subtypes and biological actions

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6 July 2018

LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway

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Oxidized LDL: diversity, patterns of recognition, and pathophysiology

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6 July 2018

Receptor-mediated vascular smooth muscle migration induced by LPA involves p38 mitogen-activated protein kinase pathway activation

1 reference

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6 July 2018

Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structure, and function of lipoproteins

1 reference

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6 July 2018

Measurement of endogenous lysophosphatidic acid by ESI-MS/MS in plasma samples requires pre-separation of lysophosphatidylcholine

1 reference

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6 July 2018

Lysophosphatidic acid-induced arterial wall remodeling: requirement of PPARgamma but not LPA1 or LPA2 GPCR.

1 reference

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6 July 2018

Regulation of blood and vascular cell function by bioactive lysophospholipids

1 reference

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6 July 2018

Metabolism and atherogenic disease association of lysophosphatidylcholine

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6 July 2018

The glycocalyx of the human umbilical vein endothelial cell: an impressive structure ex vivo but not in culture

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6 July 2018

Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation

1 reference

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6 July 2018

Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo

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6 July 2018

Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis

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6 July 2018

Biology of platelet-activating factor acetylhydrolase (PAF-AH, lipoprotein associated phospholipase A2).

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Lipoprotein-associated and secretory phospholipase A2 in cardiovascular disease: the epidemiological evidence

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6 July 2018

Lysophosphatidic acid-induced platelet shape change revealed through LPA(1-5) receptor-selective probes and albumin.

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6 July 2018

Chemokines in vascular dysfunction and remodeling.

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6 July 2018

Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure

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6 July 2018

LPA modulates monocyte migration directly and via LPA-stimulated endothelial cells

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6 July 2018

The early- and late stages in phenotypic modulation of vascular smooth muscle cells: differential roles for lysophosphatidic acid

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Roles of lysophosphatidic acid in cardiovascular physiology and disease

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6 July 2018

Lysophosphatidic acid-induced oxidized low-density lipoprotein uptake is class A scavenger receptor-dependent in macrophages.

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6 July 2018

Cyclic phosphatidic acid - a unique bioactive phospholipid

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6 July 2018

From vulnerable plaque to atherothrombosis.

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6 July 2018

Role of lysophosphatidylcholine (LPC) in atherosclerosis

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6 July 2018

Lysophosphatidic acid-induced interleukin-1 beta expression is mediated through Gi/Rho and the generation of reactive oxygen species in macrophages

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6 July 2018

Activatory properties of lysophosphatidic acid on human THP-1 cells

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6 July 2018

Regulation and biological activities of the autotaxin-LPA axis.

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6 July 2018

Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques

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6 July 2018

Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms

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6 July 2018

Lipoprotein-associated phospholipase A2.

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6 July 2018

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein

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6 July 2018

Cyclic phosphatidic acid is produced by autotaxin in blood

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6 July 2018

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

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6 July 2018

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

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6 July 2018

Vascular smooth muscle migration and proliferation in response to lysophosphatidic acid (LPA) is mediated by LPA receptors coupling to Gq

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6 July 2018

Early growth response-1 in cardiovascular pathobiology

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6 July 2018

Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets.

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6 July 2018

Atherothrombosis and high-risk plaque: part I: evolving concepts

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6 July 2018

Role of atrial natriuretic peptide in the suppression of lysophosphatydic acid-induced rat aortic smooth muscle (RASM) cell growth

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6 July 2018

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6 July 2018

Spatial and temporal dynamics of the endothelium

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Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression

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6 July 2018

Role of oxidative modifications in atherosclerosis

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6 July 2018

The accumulation of specific types of proteoglycans in eroded plaques: a role in coronary thrombosis in the absence of rupture

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6 July 2018

Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi- and NF-kappaB-dependent mechanism

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6 July 2018

Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques

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6 July 2018

Molecular regulation of vascular smooth muscle cell differentiation in development and disease

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6 July 2018

Thrombogenic and atherogenic activities of lysophosphatidic acid

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6 July 2018

Lysophosphatidic acid induces neointima formation through PPARgamma activation.

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6 July 2018

Neointimal smooth muscle cells display a proinflammatory phenotype resulting in increased leukocyte recruitment mediated by P-selectin and chemokines

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6 July 2018

The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors

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6 July 2018

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

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6 July 2018

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist

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6 July 2018

Biologic aspects of vulnerable plaque

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6 July 2018

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

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6 July 2018

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

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6 July 2018

Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate

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6 July 2018

Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids

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6 July 2018

Increased formation of lysophosphatidic acids by lysophospholipase D in serum of hypercholesterolemic rabbits.

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6 July 2018

Lysophosphatidic acid stimulates p21-activated kinase in vascular smooth muscle cells

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6 July 2018

The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium

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6 July 2018

Physiological responses to lysophosphatidic acid and related glycero-phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

A simple and highly sensitive radioenzymatic assay for lysophosphatidic acid quantification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Lysophosphatidic acid as a regulator of endothelial/leukocyte interaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Lysophosphatidic acid as a phospholipid mediator: pathways of synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Lysophosphatidic acid and intracellular signalling in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

The emerging concept of vascular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Increased platelet deposition on atherosclerotic coronary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

The binding of lysophospholipids to rat liver fatty acid-binding protein and albumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Role of the GRO family of chemokines in monocyte adhesion to MM-LDL-stimulated endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

The intima. Soil for atherosclerosis and restenosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

A family of phospholipid autacoids: occurrence, metabolism and bioactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Metabolism of lysolecithin in vivo: effects of hyperlipemia and atherosclerosis in squirrel monkeys.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Decanoyl lysophosphatidic acid induces platelet aggregation through an extracellular action. Evidence against a second messenger role for lysophosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Thromboxane A2 biosynthesis in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Minimally modified low density lipoprotein stimulates monocyte endothelial interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

A factor that activates oscillatory chloride currents in Xenopus oocytes copurifies with a subfraction of serum albumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

Platelet aggregation evoked in vitro and in vivo by phosphatidic acids and lysoderivatives: identity with substances in aged serum (DAS)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

6 July 2018

CCL20 is increased in hypercholesterolemic subjects and is upregulated by LDL in vascular smooth muscle cells: role of NF-κB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Lysophosphatidic acid receptors LPA1 and LPA3 promote CXCL12-mediated smooth muscle progenitor cell recruitment in neointima formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Regulation of cerebromicrovascular permeability by lysophosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

The role of lysophosphatidic acid receptors in phenotypic modulation of vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Signaling pathways involved in DNA synthesis and migration in response to lysophosphatidic acid and low-density lipoprotein in coronary artery smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

New mechanism of rosiglitazone to reduce neointimal hyperplasia: activation of glycogen synthase kinase-3beta followed by inhibition of MMP-9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Influence of acetylsalicylate on plasma lysophosphatidic acid level in patients with ischemic cerebral vascular diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Quantitative determination of lysophosphatidic acid by LC/ESI/MS/MS employing a reversed phase HPLC column

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Individual heterogeneity in platelet response to lysophosphatidic acid: evidence for a novel inhibitory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Upregulation of pentraxin-3 in human endothelial cells after lysophosphatidic acid exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Quantitative determination of cyclic phosphatidic acid in human serum by LC/ESI/MS/MS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Gene expression profiling for the identification of G-protein coupled receptors in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Pitavastatin inhibits lysophosphatidic acid-induced proliferation and monocyte chemoattractant protein-1 expression in aortic smooth muscle cells by suppressing Rac-1-mediated reactive oxygen species generation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Lysophosphatidic acid induces early growth response gene 1 expression in vascular smooth muscle cells: CRE and SRE mediate the transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

PPARgamma gene transfer sustains apoptosis, inhibits vascular smooth muscle cell proliferation, and reduces neointima formation after balloon injury in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Extracellular matrix molecules regulate endothelial cell migration stimulated by lysophosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Sequential activation of RhoA and FAK/paxillin leads to ATP release and actin reorganization in human endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Regulation of mitogen-activated protein kinase cascades by low density lipoprotein and lysophosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

A novel colorimetric assay for the determination of lysophosphatidic acid in plasma using an enzymatic cycling method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Mechanisms of lysophosphatidic acid-induced DNA synthesis in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Lysophosphatidic acid induction of tissue factor expression in aortic smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Electronegative LDL of FH subjects: chemical characterization and induction of chemokine release from human endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Increased production of bioactive lysophosphatidic acid by serum lysophospholipase D in human pregnancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Serum lysophosphatidic acid is produced through diverse phospholipase pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Density distribution of electronegative LDL in normolipemic and hyperlipemic subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Platelet lipid(s) bound to albumin increases endothelial electrical resistance: mimicked by LPA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Sphingosine-1-phosphate and lysophosphatidic acid stimulate endothelial cell migration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Tissue factor modulates the thrombogenicity of human atherosclerotic plaques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

The bioactive phospholipid lysophosphatidic acid is released from activated platelets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

PPAR attenuates intimal hyperplasia by inhibiting TLR4-mediated inflammation in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

SDF-1α/CXCR4 Axis Is Instrumental in Neointimal Hyperplasia and Recruitment of Smooth Muscle Progenitor Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449253

28 October 2018

Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic HCV infection is a risk of atherosclerosis. Role of HCV and HCV-related steatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carotid atherosclerosis and chronic hepatitis C: A prospective study of risk associations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence Supporting a Key Role of Lp-PLA2-Generated Lysophosphatidylcholine in Human Atherosclerotic Plaque Inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Existence of a bioactive lipid, cyclic phosphatidic acid, bound to human serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid activates nuclear factor kappa B and induces proinflammatory gene expression in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mildly oxidized low density lipoprotein rapidly stimulates via activation of the lysophosphatidic acid receptor Src family and Syk tyrosine kinases and Ca2+ influx in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid-induced platelet shape change proceeds via Rho/Rho kinase-mediated myosin light-chain and moesin phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-Activating Factor Acetylhydrolase Is Mainly Associated With Electronegative Low-Density Lipoprotein Subfraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid-induced aggregation of human and feline platelets: structure-activity relationship

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase A2 activity specific for phosphatidic acid. A possible mechanism for the production of arachidonic acid in platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human platelet aggregation induced by 1-alkyl-lysophosphatidic acid and its analogs: a new group of phospholipid mediators?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acids induce proliferation of cultured vascular smooth muscle cells from rat aorta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidic Acid and Lysophosphatidic Acid Induce Haptotactic Migration of Human Monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

α v β 3 Integrin Expression in Normal and Atherosclerotic Artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidized low density lipoprotein-mediated activation of phospholipase D in smooth muscle cells: a possible role in cell proliferation and atherogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-derived lysophosphatidic acid decreases endothelial permeability in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential immobilization and hierarchical involvement of chemokines in monocyte arrest and transmigration on inflamed endothelium in shear flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid stimulates protein kinase C isoforms alpha, beta, epsilon, and zeta in a pertussis toxin sensitive pathway in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of lysophosphatidic acid on proliferation and cytosolic Ca++ of human adult vascular smooth muscle cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane sidedness of biosynthetic pathways involved in the production of lysophosphatidic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homo- and hetero-dimerization of LPA/S1P receptors, OGR1 and GPR4

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid stimulation of platelets rapidly induces Ca2+-dependent dephosphorylation of cofilin that is independent of dense granule secretion and aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: proposal of a plasma sample preparation method for laboratory testing of these lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of platelet thrombus formation by chlorpromazine acting to diminish haemolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2012.02021.X

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

0 references

Sitelinks

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