(Q34247703)

31 July 2017

title

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis (English)

1 reference

31 July 2017

0 references

1 reference

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Narender Nath

1 reference

31 July 2017

Musfiquidin Khan

1 reference

31 July 2017

Manjeet K Paintlia

1 reference

31 July 2017

Inderjit Singh

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31 July 2017

Md Nasrul Hoda

1 reference

31 July 2017

Shailendra Giri

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31 July 2017

language of work or name

English

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publication date

1 June 2009

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31 July 2017

published in

Journal of Immunology

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31 July 2017

volume

182

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31 July 2017

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31 July 2017

page(s)

8005-8014

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Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype

31 July 2017

cites work

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

6 July 2018

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6 July 2018

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6 July 2018

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Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Insulin resistance as a therapeutic target for improved endothelial function: metformin

6 July 2018

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Metformin and lactic acidosis: cause or coincidence? A review of case reports

6 July 2018

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6 July 2018

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Diverse targets for intervention during inflammatory and neurodegenerative phases of multiple sclerosis

6 July 2018

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The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism

6 July 2018

1 reference

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The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

6 July 2018

1 reference

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Role of AMP-activated protein kinase in mechanism of metformin action

6 July 2018

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T- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis

6 July 2018

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Metformin reverses fatty liver disease in obese, leptin-deficient mice

6 July 2018

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Assessment of animal models for MS and demyelinating disease in the design of rational therapy

6 July 2018

1 reference

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Adhesion molecule expression and regulation on cells of the central nervous system

6 July 2018

1 reference

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The cytokine storm in multiple sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease

6 July 2018

1 reference

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6 July 2018

1 reference

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The blood-brain barrier and multiple sclerosis

6 July 2018

1 reference

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Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

6 July 2018

1 reference

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Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers

6 July 2018

1 reference

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Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis.

6 July 2018

1 reference

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Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression

6 July 2018

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Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis

6 July 2018

1 reference

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The T lymphocyte in experimental allergic encephalomyelitis

6 July 2018

1 reference

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Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome

6 July 2018

1 reference

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Functional analysis of the human vascular cell adhesion molecule 1 promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Metformin administration improves endothelial function in women with polycystic ovary syndrome

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis--an intravital microscopy study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Increased plasma concentration of macrophage migration inhibitory factor (MIF) and MIF mRNA in mononuclear cells in the obese and the suppressive action of metformin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

The differential effects of metformin on markers of endothelial activation and inflammation in subjects with impaired glucose tolerance: a placebo-controlled, randomized clinical trial

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Metformin attenuates blood lipid peroxidation and potentiates antioxidant defense in high fructose-fed rats

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Endotoxin-induced alterations of lipid and fatty acid compositions in rat liver peroxisomes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: relative roles of interleukin (IL)-4 and IL-10.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965405

Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes

28 October 2018

1 reference

12 December 2020

Expression of ICAM-1, VCAM-1, L-selectin, and leukosialin in the mouse central nervous system during the induction and remission stages of experimental allergic encephalomyelitis

1 reference

12 December 2020

Immunology of multiple sclerosis

1 reference

12 December 2020

Autoimmune diseases: genes, bugs and failed regulation

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0803563

1 reference

31 July 2017

1 reference

31 July 2017

1 reference