(Q34243160)

31 July 2017

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title

HERG K+ channels: friend and foe. (English)

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31 July 2017

J I Vandenberg

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31 July 2017

B D Walker

series ordinal

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31 July 2017

T J Campbell

series ordinal

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31 July 2017

language of work or name

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1 May 2001

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Trends in Pharmacological Sciences

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

240-246

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The long QT syndromes: genetic basis and clinical implications

31 July 2017

cites work

1 reference

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7 January 2021

Molecular genetic insights into cardiovascular disease

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7 January 2021

Genetic and molecular basis of cardiac arrhythmias; impact on clinical management. Study group on molecular basis of arrhythmias of the working group on arrhythmias of the european society of cardiology

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7 January 2021

Heart failure: the electrophysiologic connection

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7 January 2021

Cardiac ionic currents and acute ischemia: from channels to arrhythmias

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7 January 2021

Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction

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7 January 2021

The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology

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7 January 2021

Images in clinical medicine. Congenital long-QT syndrome

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7 January 2021

A family of potassium channel genes related to eag in Drosophila and mammals

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7 January 2021

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

1 reference

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7 January 2021

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

1 reference

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7 January 2021

The inward rectification mechanism of the HERG cardiac potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

1 reference

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7 January 2021

Cyclic AMP regulates the HERG K(+) channel by dual pathways

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7 January 2021

A common polymorphism associated with antibiotic-induced cardiac arrhythmia

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7 January 2021

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

1 reference

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7 January 2021

Survey of the coding region of the HERG gene in long QT syndrome reveals six novel mutations and an amino acid polymorphism with possible phenotypic effects

1 reference

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7 January 2021

QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience

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7 January 2021

Drug-induced torsade de pointes: from molecular biology to bedside.

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7 January 2021

Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell

1 reference

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7 January 2021

Sodium pentobarbital reduces transmural dispersion of repolarization and prevents torsades de Pointes in models of acquired and congenital long QT syndrome

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7 January 2021

A third class of anti-arrhythmic action. Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscle, of MJ 1999 and AH 3474

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7 January 2021

The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis

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7 January 2021

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7 January 2021

Cardiovascular drugs. Dofetilide

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7 January 2021

Ibutilide and the treatment of atrial arrhythmias. A new drug--almost unheralded--is now available to US physicians

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7 January 2021

Risk of torsades de pointes with non-cardiac drugs. Doctors need to be aware that many drugs can cause qt prolongation

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7 January 2021

Clinical features and basic mechanisms of quinidine-induced arrhythmias

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7 January 2021

QT-interval prolonging drugs: mechanisms and clinical relevance of their arrhythmogenic hazards

1 reference

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7 January 2021

Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias

1 reference

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7 January 2021

Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Molecular determinants of dofetilide block of HERG K+ channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Probing the interaction between inactivation gating and Dd-sotalol block of HERG.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Structure and dynamics of K channel pore-lining helices: a comparative simulation study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

Blocker protection in the pore of a voltage-gated K+ channel and its structural implications

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

A structural basis for drug-induced long QT syndrome

1 reference

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7 January 2021

Electrophysiological mechanism of the characteristic electrocardiographic morphology of torsade de pointes tachyarrhythmias in the long-QT syndrome: detailed analysis of ventricular tridimensional activation patterns

1 reference

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7 January 2021

The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901662-X

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

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7 January 2021

10.1016/S0165-6147(00)01662-X

Identifiers

DOI

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31 July 2017

1 reference