(Q34126257)

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Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

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9 January 2020

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16284649%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

phosphorylation

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insulin resistance

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Katsutarō Morino

1

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9 January 2020

9

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9 January 2020

Gerald I. Shulman

12

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9 January 2020

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Sylvie Dufour

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9 January 2020

Susanne Neschen

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Susanne Neschen

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9 January 2020

4

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Douglas Befroy

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9 January 2020

10

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Saki Sono

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9 January 2020

11

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Marc Pypaert

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9 January 2020

Kitt Falk Petersen

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Kitt Falk Petersen

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9 January 2020

author name string

Jared Frattini

5

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9 January 2020

Nadine Shatzkes

6

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9 January 2020

Morris F White

8

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9 January 2020

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10 November 2005

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9 January 2020

Journal of Clinical Investigation

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9 January 2020

115

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9 January 2020

12

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9 January 2020

3587-3593

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16284649%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

A central role for JNK in obesity and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Prevention of fat-induced insulin resistance by salicylate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Cellular mechanisms of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Protein Kinase C Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation Requires Serine 612

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

The effect of non-insulin-dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Mechanisms of fatty acid-induced inhibition of glucose uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

5 July 2018

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280967

28 October 2018

Quantitative analysis of total mitochondrial DNA: Competitive polymerase chain reaction versus real-time polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16284649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A short questionnaire for the measurement of habitual physical activity in epidemiological studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16284649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A microfluorometric method for the determination of free fatty acids in plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16284649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose metabolism during the menstrual cycle. Assessment with the euglycemic, hyperinsulinemic clamp

1 reference

https://pubmed.ncbi.nlm.nih.gov/16284649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16284649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/16284649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16284649

12 December 2020

based on heuristic

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Identifiers

10.1172/JCI25151

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16284649%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

release_kaxzt4w27zffde7d6avdesj26a

1 reference

https://api.fatcat.wiki/v0/release/kaxzt4w27zffde7d6avdesj26a

24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16284649%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16284649%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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