(Q34194287)

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The RAG proteins in V(D)J recombination: more than just a nuclease

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Europe PubMed Central

The RAG proteins in V(D)J recombination: more than just a nuclease (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

M J Sadofsky

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Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

1 April 2001

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Europe PubMed Central

PubMed publication ID

31 July 2017

Nucleic Acids Research

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Europe PubMed Central

PubMed publication ID

31 July 2017

29

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Europe PubMed Central

PubMed publication ID

31 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1399-1409

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Europe PubMed Central

PubMed publication ID

31 July 2017

A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination.

1 reference

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5 July 2018

Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination

1 reference

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5 July 2018

Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination

1 reference

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5 July 2018

The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination

1 reference

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5 July 2018

Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors

1 reference

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5 July 2018

N-terminal RAG1 frameshift mutations in Omenn's syndrome: internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role in vivo for the N-terminal domains.

1 reference

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Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

1 reference

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Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

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Error-prone candidates vie for somatic mutation

1 reference

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Genetic modulation of T cell receptor gene segment usage during somatic recombination

1 reference

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5 July 2018

Evolution of the recombination signal sequences in the Ig heavy-chain variable region locus of mammals

1 reference

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5 July 2018

The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire

1 reference

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5 July 2018

Activation of V(D)J recombination induces the formation of interlocus joints and hybrid joints in scid pre-B-cell lines

1 reference

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5 July 2018

Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Postcleavage sequence specificity in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

1 reference

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A mechanistic basis for Mre11-directed DNA joining at microhomologies

1 reference

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Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex

1 reference

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5 July 2018

The old and the restless

1 reference

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Recombination-activating genes, transposition, and the lymphoid-specific combinatorial immune system: a common evolutionary connection

1 reference

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Three-dimensional clustering of human RAG2 gene mutations in severe combined immune deficiency.

1 reference

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5 July 2018

DNA double strand break repair in mammalian cells

1 reference

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Sloppier copier DNA polymerases involved in genome repair

1 reference

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Unique and unprecedented recombination mechanisms in class switching

1 reference

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5 July 2018

A highly ordered structure in V(D)J recombination cleavage complexes is facilitated by HMG1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Mechanistic basis for coding end sequence effects in the initiation of V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.

1 reference

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5 July 2018

RAG and RAG defects

1 reference

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The liaison of isotype class switch and mismatch repair: an illegitimate affair

1 reference

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5 July 2018

V(D)J recombination: on the cutting edge

1 reference

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Basal divergences in birds and the phylogenetic utility of the nuclear RAG-1 gene

1 reference

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5 July 2018

A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

1 reference

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The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

1 reference

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5 July 2018

Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Intermolecular V(D)J recombination is prohibited specifically at the joining step

1 reference

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Somatic hypermutation and the three R's: repair, replication and recombination

1 reference

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5 July 2018

Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

RAG1 and RAG2 cooperate in specific binding to the recombination signal sequence in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

1 reference

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5 July 2018

The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

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Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

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DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

1 reference

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5 July 2018

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 reference

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5 July 2018

Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly

1 reference

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5 July 2018

V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

1 reference

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5 July 2018

Functional analysis of coordinated cleavage in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

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5 July 2018

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

1 reference

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5 July 2018

The effect of Me2+ cofactors at the initial stages of V(D)J recombination

1 reference

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5 July 2018

Partial V(D)J recombination activity leads to Omenn syndrome

1 reference

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A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration

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5 July 2018

RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution

1 reference

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5 July 2018

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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5 July 2018

Complementation of V(D)J recombination deficiency in RAG-1(-/-) B cells reveals a requirement for novel elements in the N-terminus of RAG-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The end-joining reaction in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Nucleotide deletion and P addition in V(D)J recombination: a determinant role of the coding-end sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Stimulation of V(D)J cleavage by high mobility group proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Initiation of V(D)J recombination in vivo: role of recombination signal sequences in formation of single and paired double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Cryptic signals and the fidelity of V(D)J joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Recent advances in understanding V(D)J recombination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Characterization and expression of the recombination activating genes (rag1 and rag2) of zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

A complex of RAG-1 and RAG-2 proteins persists on DNA after single-strand cleavage at V(D)J recombination signal sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Primordial emergence of the recombination activating gene 1 (RAG1): sequence of the complete shark gene indicates homology to microbial integrases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Mechanism of V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Genetic evidence that the RAG1 protein directly participates in V(D)J recombination through substrate recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

P nucleotides in V(D)J recombination: a fine-structure analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Characterization and expression of recombination activating genes (RAG-1 and RAG-2) in Xenopus laevis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Coding end sequence can markedly affect the initiation of V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Expression and V(D)J recombination activity of mutated RAG-1 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Characterization of broken DNA molecules associated with V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Analysis of regions of RAG-2 important for V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Definition of a core region of RAG-2 that is functional in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Initiation of V(D)J recombination in a cell-free system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The recombination activating gene 1 (RAG1) of rainbow trout (Oncorhynchus mykiss): cloning, expression, and phylogenetic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Formation and resolution of double-strand break intermediates in V(D)J rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Somatic generation of antibody diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

The V(D)J recombination activating gene, RAG-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Cutting and closing without recombination in V(D)J joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Transpositional recombination: mechanistic insights from studies of mu and other elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

5 July 2018

Characterization of a mutation of bacteriophage lambda integrase. Putative role in core binding and strand exchange for a conserved residue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

N-terminal truncated human RAG1 proteins can direct T-cell receptor but not immunoglobulin gene rearrangements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Characterization of the recombinase activating gene-1 and 2 locus in the Japanese pufferfish, Fugu rubripes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Antigen receptor gene rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Rejoining of DNA by the RAG1 and RAG2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Recombination activating gene-1 of the opossum Monodelphis domestica.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Recombination activating genes-1 and -2 of the rabbit: cloning and characterization of germline and expressed genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31291

28 October 2018

Metal Activation of Enzymes in Nucleic Acid Biochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A zinc-binding domain involved in the dimerization of RAG1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Joining-deficient RAG1 mutants block V(D)J recombination in vivo and hairpin opening in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermolecular V(D)J recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ragtime jumping

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of a large region of RAG1 that is important for coimmunoprecipitation of RAG2

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathymic restriction and peripheral expansion of the T-cell repertoire in Omenn syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel strand exchanges in V(D)J recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mu transpositional recombination: donor DNA cleavage and strand transfer in trans by the Mu transposase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAG1/2-mediated resolution of transposition intermediates: two pathways and possible consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VDJ recombination: a transposase goes to work

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DNA-bending protein, HMG1, is required for correct cleavage of 23 bp recombination signal sequences by recombination activating gene proteins in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RAG1/RAG2 complex constitutes a 3' flap endonuclease: implications for junctional diversity in V(D)J and transpositional recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-free V(D)J recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interwoven architecture of the Mu transposase couples DNA synapsis to catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11266539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/29.7.1399

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

0 references

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