(Q34185656)

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Cellular stress response pathways and ageing: intricate molecular relationships

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Europe PubMed Central

Cellular stress response pathways and ageing: intricate molecular relationships (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

Nektarios Tavernarakis

2

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Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Nikos Kourtis

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

17 May 2011

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Europe PubMed Central

PubMed publication ID

31 July 2017

The EMBO Journal

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Europe PubMed Central

PubMed publication ID

31 July 2017

30

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2520-2531

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

1 reference

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5 July 2018

Autophagy and the Integrated Stress Response

1 reference

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5 July 2018

Widespread protein aggregation as an inherent part of aging in C. elegans

1 reference

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5 July 2018

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

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5 July 2018

Heat shock factors: integrators of cell stress, development and lifespan.

1 reference

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5 July 2018

mTORC1 links protein quality and quantity control by sensing chaperone availability

1 reference

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5 July 2018

Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity

1 reference

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5 July 2018

The genetics of ageing

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5 July 2018

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

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5 July 2018

The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans

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5 July 2018

HSF1-controlled and age-associated chaperone capacity in neurons and muscle cells of C. elegans.

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5 July 2018

Chaperone-mediated autophagy: selectivity pays off.

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5 July 2018

DNA Damage, Aging, and Cancer

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5 July 2018

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

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5 July 2018

mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex

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5 July 2018

ER and aging-Protein folding and the ER stress response

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5 July 2018

The proteasomal system.

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5 July 2018

Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

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5 July 2018

Aging augments mitochondrial susceptibility to heat stress

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5 July 2018

Autophagy and cell death in model organisms

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5 July 2018

DNA damage and ageing: new-age ideas for an age-old problem

1 reference

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5 July 2018

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

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5 July 2018

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

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5 July 2018

Single-strand break repair and genetic disease

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5 July 2018

Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling

1 reference

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5 July 2018

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

1 reference

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5 July 2018

Premature aging in mice activates a systemic metabolic response involving autophagy induction.

1 reference

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5 July 2018

Autophagy fights disease through cellular self-digestion

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5 July 2018

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

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5 July 2018

Regulation of proteasome-mediated protein degradation during oxidative stress and aging

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5 July 2018

Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects

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5 July 2018

Endoplasmic reticulum stress in disease pathogenesis

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5 July 2018

Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers

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5 July 2018

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

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5 July 2018

Hormesis in aging

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5 July 2018

Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

1 reference

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5 July 2018

Changes in the level and distribution of Ku proteins during cellular senescence.

1 reference

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5 July 2018

Trends in oxidative aging theories

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5 July 2018

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

1 reference

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5 July 2018

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

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5 July 2018

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

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5 July 2018

The study of Golgi apparatus in Alzheimer's disease

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5 July 2018

Reduced eIF2alpha phosphorylation and increased proapoptotic proteins in aging

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ER stress and diseases.

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5 July 2018

Heat shock factor 1 as a coordinator of stress and developmental pathways

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5 July 2018

The mechanics of base excision repair, and its relationship to aging and disease

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5 July 2018

Mediators of endoplasmic reticulum stress-induced apoptosis

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5 July 2018

Opposing activities protect against age-onset proteotoxicity

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5 July 2018

Endoplasmic reticulum stress triggers autophagy

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5 July 2018

UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair

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5 July 2018

Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response

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5 July 2018

The effect of aging on the chaperone concentrations in the hepatic, endoplasmic reticulum of male rats: the possible role of protein misfolding due to the loss of chaperones in the decline in physiological function seen with age

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5 July 2018

Loss of autophagy in the central nervous system causes neurodegeneration in mice

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5 July 2018

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

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5 July 2018

Protein folding in the endoplasmic reticulum and the unfolded protein response.

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5 July 2018

Progressively impaired proteasomal capacity during terminal plasma cell differentiation

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5 July 2018

Proteasome function in aging and oxidative stress: implications in protein maintenance failure

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5 July 2018

Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.

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5 July 2018

Heat shock proteins in cancer: chaperones of tumorigenesis

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5 July 2018

TOR signaling in growth and metabolism

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5 July 2018

Molecular mechanisms of mammalian global genome nucleotide excision repair.

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5 July 2018

Inhibition of DNA binding by differential sumoylation of heat shock factors

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5 July 2018

ER stress and neurodegenerative diseases

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5 July 2018

From acute ER stress to physiological roles of the Unfolded Protein Response

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5 July 2018

Aged human skin removes UVB-induced pyrimidine dimers from the epidermis more slowly than younger adult skin in vivo.

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5 July 2018

Autophagy: molecular machinery for self-eating

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5 July 2018

Sick chaperones, cellular stress, and disease

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5 July 2018

Opinion: What is the role of protein aggregation in neurodegeneration?

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5 July 2018

Golgi structure in stress sensing and apoptosis

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5 July 2018

Cellular environment facilitates protein accumulation in aged rat hippocampus.

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5 July 2018

The mammalian unfolded protein response

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5 July 2018

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

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5 July 2018

Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress

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5 July 2018

Superoxide dismutase evolution and life span regulation

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5 July 2018

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

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5 July 2018

Autophagy: many paths to the same end.

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5 July 2018

Aging intervention, prevention, and therapy through hormesis

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5 July 2018

Slowing down aging from within: mechanistic aspects of anti-aging hormetic effects of mild heat stress on human cells

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5 July 2018

Gene regulation and DNA damage in the ageing human brain

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5 July 2018

Role of immune responsiveness and DNA repair capacity genes in ageing

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5 July 2018

Hormesis: from marginalization to mainstream: a case for hormesis as the default dose-response model in risk assessment

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5 July 2018

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

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5 July 2018

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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Myocyte aging and mitochondrial turnover

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5 July 2018

Endogenous DNA damage in humans: a review of quantitative data

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5 July 2018

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

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5 July 2018

Heat shock proteins and aging in Drosophila melanogaster

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5 July 2018

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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5 July 2018

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

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5 July 2018

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

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5 July 2018

"Slip, sliding away": phospholipase D and the Golgi apparatus

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5 July 2018

Autophagy genes are essential for dauer development and life-span extension in C. elegans

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5 July 2018

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

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5 July 2018

Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of Mammalian proteasomes

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5 July 2018

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1

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5 July 2018

Quality control in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Subpathways of nucleotide excision repair and their regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Impairment of proteasome structure and function in aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

A mitochondrial specific stress response in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Dynamic remodeling of transcription complexes by molecular chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Large genome rearrangements as a primary cause of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

DNA oligonucleotide treatment corrects the age-associated decline in DNA repair capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Longevity and aging: beneficial effects of exposure to mild stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Molecular chaperones and the aging process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Signaling pathways regulating Golgi structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Ultraviolet radiation alters the phosphorylation of RNA polymerase II large subunit and accelerates its proteasome-dependent degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Proteasome inhibitors: from research tools to drug candidates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Parkinson's disease, pesticides and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

The age of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Expression of UMP1 is inducible by DNA damage and required for resistance of S. cerevisiae cells to UV light

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

ER stress response: getting the UPR hand on misfolded proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Mechanisms and implications of the age-associated decrease in DNA repair capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Activation of heat shock factor 1 by hyperosmotic or hypo-osmotic stress is drastically attenuated in normal human fibroblasts during senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Age-related decline in chaperone-mediated autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Mutation frequency and specificity with age in liver, bladder and brain of lacI transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Mitotic misregulation and human aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Possible involvement of proteasome inhibition in aging: implications for oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Protein folding in the ER.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

The age-related accumulation of protein carbonyl in rat liver correlates with the age-related decline in liver proteolytic activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Heat shock proteins as cellular lifeguards

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Frequency of spontaneous chromosome aberrations in mice: effects of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Molecularchaperones as HSF1-specific transcriptional repressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Rapid accumulation of genome rearrangements in liver but not in brain of old mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Repression of human heat shock factor 1 activity at control temperature by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Instability and decay of the primary structure of DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

DNA repair and aging in basal cell carcinoma: a molecular epidemiology study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Deletion mutations in the hprt gene of T-lymphocytes as a biomarker for genomic rearrangements important in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

UV-induced unscheduled DNA synthesis in fibroblasts of aging inbred rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

The occurrence of chemically induced hormesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

The heat-shock proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

5 July 2018

Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Effect of aging and anti-aging caloric restriction on the endocrine regulation of rat liver autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

A ubiquitin stress response induces altered proteasome composition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Autophagy regulates ageing in C. elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Decreased expression of DNA repair proteins Ku70 and Mre11 is associated with aging and may contribute to the cellular senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Fragmentation of Golgi apparatus of nigral neurons with alpha-synuclein-positive inclusions in patients with Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Reduced DNA gap repair in aging rat neuronal extracts and its restoration by DNA polymerase beta and DNA-ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Mitochondrial alterations in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Mitochondrial respiratory deficiencies signal up-regulation of genes for heat shock proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Hormesis in Caenorhabditis elegans dauer-defective mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Age-related base excision repair activity in mouse brain and liver nuclear extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Ras signalling on the endoplasmic reticulum and the Golgi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Age-dependent declines in proteasome activity in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Age-related changes in the regulation of autophagic proteolysis in rat isolated hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Alteration of rat liver 20S proteasome activities by age and food restriction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Reversible phosphorylation of eukaryotic initiation factor 2 alpha in response to endoplasmic reticular signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155297

28 October 2018

Age-related alterations in the activation of heat shock transcription factor 1 in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of age on the formation and repair of UV photoproducts in human skin in situ

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired proteasome function in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A time-dependent phase shift in the mammalian unfolded protein response

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific changes of DNA repair protein Ku and mtHSP70 in aging rats and their retardation by caloric restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeostatic regulation of the proteasome via an Rpn4-dependent feedback circuit

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy, heterophagy, microautophagy and crinophagy as the means for intracellular degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased chromosomal aberrations in first metaphases of cells isolated from the kidneys of aged mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of age on formation and elimination of autophagic vacuoles in mouse hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of aging on protein import into cardiac mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary self-selection can compensate an age-related decrease of rat liver 20 S proteasome activity observed with standard diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress-inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased proteasome-mediated degradation in T cells from the elderly: A role in immune senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of age on DNA binding of the ku protein in irradiated human peripheral blood mononuclear cells (PBMC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosome Aberrations in Liver Cells in Relation to the Somatic Mutation Theory of Aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis: from the lysosome to ubiquitin and the proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related loss of stress-induced nuclear proteasome activation is due to low PARP-1 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chaperone-Mediated Autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21587205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormesis: from marginalization to mainstream

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/EMBOJ.2011.162

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

0 references

Sitelinks

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