(Q34180376)

31 July 2017

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title

Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks (English)

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31 July 2017

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R H Lenox

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31 July 2017

Le Wang

series ordinal

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31 July 2017

language of work or name

English

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publication date

1 February 2003

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

135-144

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The impact of the discovery of lithium on psychiatric thought and practice in the USA and Europe.

31 July 2017

cites work

1 reference

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Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants.

21 January 2018

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Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences

21 January 2018

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Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

21 January 2018

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Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slices

21 January 2018

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Evidence that a proconvulsant action of lithium is mediated by inhibition of myo-inositol phosphatase in mouse brain

21 January 2018

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Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance

21 January 2018

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Lithium and myo-inositol homeostasis

21 January 2018

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Long-term action of lithium: a role for transcriptional and posttranscriptional factors regulated by protein kinase C.

21 January 2018

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Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol

21 January 2018

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AP-1 and NF-κ B stimulated by carbachol in human neuroblastoma SH-SY5Y cells are differentially sensitive to inhibition by lithium

21 January 2018

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Increased membrane-associated protein kinase C activity and translocation in blood platelets from bipolar affective disorder patients

21 January 2018

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Increased association of brain protein kinase C with the receptor for activated C kinase-1 (RACK1) in bipolar affective disorder

21 January 2018

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Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification

21 January 2018

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LEF-1/TCF Proteins Mediate Wnt-Inducible Transcription from the Xenopus Nodal-Related 3 Promoter

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A β-catenin/XTcf-3 complex binds to thesiamois promoter to regulate dorsal axis specification in Xenopus

21 January 2018

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LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

21 January 2018

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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Identification of c-MYC as a target of the APC pathway

21 January 2018

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Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion

21 January 2018

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BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents

21 January 2018

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L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

21 January 2018

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Activation of the Wnt signaling pathway: a molecular mechanism for lithium action

21 January 2018

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A molecular mechanism for the effect of lithium on development

21 January 2018

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The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth

21 January 2018

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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

21 January 2018

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Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

21 January 2018

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Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations.

21 January 2018

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Lithium Reduces Tau Phosphorylation by Inhibition of Glycogen Synthase Kinase-3

21 January 2018

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Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons

21 January 2018

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Glycogen synthase kinase 3: an emerging therapeutic target

21 January 2018

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Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C.

21 January 2018

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Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner

21 January 2018

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Wnt signaling and heterotrimeric G-proteins: strange bedfellows or a classic romance?

21 January 2018

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G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.

21 January 2018

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Regulation of signal transduction pathways and gene expression by mood stabilizers and antidepressants

21 January 2018

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Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

21 January 2018

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Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

21 January 2018

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Munc18-1 promotes large dense-core vesicle docking

21 January 2018

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Lithium ions enhance cysteine string protein gene expression in vivo and in vitro

21 January 2018

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The DnaJ-like cysteine string protein and exocytotic neurotransmitter release

21 January 2018

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Evoked transmitter release at neuromuscular junctions in wild type and cysteine string protein null mutant larvae of Drosophila.

21 January 2018

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The MARCKS brothers: a family of protein kinase C substrates

21 January 2018

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GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Overexpression of myristoylated alanine-rich C-kinase substrate enhances activation of phospholipase D by protein kinase C in SK-N-MC human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

MARCKS deficiency in mice leads to abnormal brain development and perinatal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Nonmyristoylated MARCKS complements some but not all of the developmental defects associated with MARCKS deficiency in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Regulation of angiotensin II-induced neuromodulation by MARCKS in brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: transgenic rescue and interactions with gene background

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Transcriptional down-regulation of MARCKS gene expression in immortalized hippocampal cells by lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A common mechanism of action for three mood-stabilizing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Transcriptional regulation of mouse MARCKS promoter in immortalized hippocampal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

The biology of left-handed Z-DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Analysis of gene expression with cDNA microarrays in rat brain after 7 and 42 days of oral lithium administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Linking the genes: inferring quantitative gene networks from microarray data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Genome-wide location and function of DNA binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A regulatory gene network that directs micromere specification in the sea urchin embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Outcome after rapid vs gradual discontinuation of lithium treatment in bipolar disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Nuclear lipid signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Lithium reduces the accumulation of inositol polyphosphate second messengers following cholinergic stimulation of cerebral cortex slices

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Concurrent measures of protein kinase C and phosphoinositides in lithium-treated bipolar patients and healthy individuals: a preliminary study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Increase in the pool size of releasable synaptic vesicles by the activation of protein kinase C in goldfish retinal bipolar cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Activation of protein kinase C-alpha and translocation of the myristoylated alanine-rich C-kinase substrate correlate with phorbol ester-enhanced noradrenaline release from SH-SY5Y human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Localization of the MARCKS (87 kDa) protein, a major specific substrate for protein kinase C, in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Obligatory role of protein kinase Cbeta and MARCKS in vesicular trafficking in living neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Phorbol ester- and retinoic acid-induced regulation of the protein kinase C substrate MARCKS in immortalized hippocampal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001306

1 reference

Dimensions Publication ID

31 July 2017

1039606038

0 references

1 reference