(Q34096366)

31 July 2017

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title

Principles and challenges of genomewide DNA methylation analysis (English)

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31 July 2017

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Peter W Laird

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31 July 2017

language of work or name

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1 March 2010

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31 July 2017

published in

Nature Reviews Genetics

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

191-203

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Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis

31 July 2017

cites work

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Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription.

31 March 2020

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Global analysis of genetic, epigenetic and transcriptional polymorphisms in Arabidopsis thaliana using whole genome tiling arrays

31 March 2020

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The DNA methylation paradox

31 March 2020

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Gene body-specific methylation on the active X chromosome

31 March 2020

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Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

31 March 2020

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An Arabidopsis jmjC domain protein protects transcribed genes from DNA methylation at CHG sites.

31 March 2020

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

31 March 2020

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Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome

31 March 2020

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Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method

31 March 2020

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Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M.

31 March 2020

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Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression

31 March 2020

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Restriction landmark genomic scanning method and its various applications

31 March 2020

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31 March 2020

12 December 2020

A microarray-based method for detecting methylated loci

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Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays

31 March 2020

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Chromatin profiling using targeted DNA adenine methyltransferase

31 March 2020

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Methylation profiling of CpG islands in human breast cancer cells

31 March 2020

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Analysis of chromatin-immunopurified MeCP2-associated fragments

31 March 2020

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From genomics to epigenomics: a loftier view of life

31 March 2020

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Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning

31 March 2020

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Human DNA methylomes at base resolution show widespread epigenomic differences

31 March 2020

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Highly integrated single-base resolution maps of the epigenome in Arabidopsis

31 March 2020

1 reference

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

31 March 2020

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Genome-scale DNA methylation maps of pluripotent and differentiated cells

31 March 2020

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

31 March 2020

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

31 March 2020

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The power and the promise of DNA methylation markers

31 March 2020

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Genome-wide approaches to studying chromatin modifications

31 March 2020

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DNA methylation: a profile of methods and applications

31 March 2020

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Genome-wide high throughput analysis of DNA methylation in eukaryotes

31 March 2020

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The emerging science of epigenomics

31 March 2020

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The methylome: approaches for global DNA methylation profiling

31 March 2020

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Detection and interpretation of altered methylation patterns in cancer cells

31 March 2020

1 reference

Emerging technologies for genome-wide DNA methylation profiling in cancer

31 March 2020

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Epigenomics: mapping the methylome

31 March 2020

1 reference

Finding the fifth base: genome-wide sequencing of cytosine methylation.

31 March 2020

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Applying whole-genome studies of epigenetic regulation to study human disease

31 March 2020

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Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome.

31 March 2020

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Locking in on the human methylome.

31 March 2020

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Reduced-representation methylation mapping

31 March 2020

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Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3

31 March 2020

1 reference

DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues

31 March 2020

1 reference

DNA methylation at a CCGG sequence in the large intron of the rabbit beta-globin gene: tissue-specific variations

31 March 2020

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Methylation of somatic vs germ cell DNAs analyzed by restriction endonuclease digestions

31 March 2020

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Analysis of Calf-Thymus Satellite DNA: Evidence for Specific Methylation of Cytosine in C-G Sequences

31 March 2020

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Identification of DNA methylation differences during tumorigenesis by methylation-sensitive arbitrarily primed polymerase chain reaction

31 March 2020

1 reference

Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS).

31 March 2020

1 reference

High-throughput methylation profiling by MCA coupled to CpG island microarray

31 March 2020

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Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling

31 March 2020

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Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma

31 March 2020

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Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer.

31 March 2020

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Differential methylation hybridization: profiling DNA methylation with a high-density CpG island microarray

31 March 2020

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Purification of CpG islands using a methylated DNA binding column

31 March 2020

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DNA methylation profiling identifies CG methylation clusters in Arabidopsis genes

31 March 2020

1 reference

Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine

31 March 2020

1 reference

Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays

31 March 2020

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Identification of novel high-frequency DNA methylation changes in breast cancer

31 March 2020

1 reference

Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets.

31 March 2020

1 reference

Comprehensive high-throughput arrays for relative methylation (CHARM).

31 March 2020

1 reference

MMASS: an optimized array-based method for assessing CpG island methylation

31 March 2020

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Microarray-based DNA methylation profiling: technology and applications

31 March 2020

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Large-scale structure of genomic methylation patterns

31 March 2020

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Comparative isoschizomer profiling of cytosine methylation: the HELP assay

31 March 2020

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High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers.

31 March 2020

1 reference

Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver

31 March 2020

1 reference

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

31 March 2020

1 reference

High-resolution profiling of histone methylations in the human genome

31 March 2020

1 reference

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

31 March 2020

1 reference

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

31 March 2020

1 reference

A chromatin landmark and transcription initiation at most promoters in human cells

31 March 2020

1 reference

Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

31 March 2020

1 reference

The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide

31 March 2020

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

31 March 2020

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Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

31 March 2020

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Evidence for an instructive mechanism of de novo methylation in cancer cells.

31 March 2020

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Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes

31 March 2020

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Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

31 March 2020

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Epigenetic profiling at mouse imprinted gene clusters reveals novel epigenetic and genetic features at differentially methylated regions

31 March 2020

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High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array

31 March 2020

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Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome

31 March 2020

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Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

31 March 2020

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Epigenetics of human T cells during the G0-->G1 transition.

31 March 2020

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Genome-wide screen of promoter methylation identifies novel markers in melanoma.

31 March 2020

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Developmental programming of CpG island methylation profiles in the human genome

31 March 2020

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A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis

31 March 2020

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Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR.

31 March 2020

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Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia

31 March 2020

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Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.

31 March 2020

1 reference

Engineering a high-affinity methyl-CpG-binding protein

31 March 2020

1 reference

Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer

31 March 2020

1 reference

The MIRA method for DNA methylation analysis

31 March 2020

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High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer

31 March 2020

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Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.

31 March 2020

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Discovery of bisulfite-mediated cytosine conversion to uracil, the key reaction for DNA methylation analysis--a personal account

31 March 2020

1 reference

Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues

31 March 2020

1 reference

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

31 March 2020

1 reference

High sensitivity mapping of methylated cytosines

31 March 2020

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Cytosine methylation: quantitation by automated genomic sequencing and GENESCAN analysis.

31 March 2020

1 reference

DNA methylation profiling of human chromosomes 6, 20 and 22

31 March 2020

1 reference

Tumour class prediction and discovery by microarray-based DNA methylation analysis

31 March 2020

1 reference

Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis

31 March 2020

1 reference

Genome-wide, high-resolution DNA methylation profiling using bisulfite-mediated cytosine conversion

31 March 2020

1 reference

High-throughput DNA methylation profiling using universal bead arrays

31 March 2020

1 reference

Human embryonic stem cells have a unique epigenetic signature

31 March 2020

1 reference

GoldenGate assay for DNA methylation profiling

31 March 2020

1 reference

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

31 March 2020

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Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns

31 March 2020

1 reference

DNA methylation signatures within the human brain

31 March 2020

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DNA methylation and gene expression differences in children conceived in vitro or in vivo

31 March 2020

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A microarray-based DNA methylation study of glioblastoma multiforme

31 March 2020

1 reference

Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

31 March 2020

1 reference

Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions

31 March 2020

1 reference

Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling

31 March 2020

1 reference

Genome-wide DNA methylation profiling using Infinium® assay

31 March 2020

1 reference

Whole genome genotyping technologies on the BeadArray platform

31 March 2020

1 reference

Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA.

31 March 2020

1 reference

Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing.

31 March 2020

1 reference

Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

31 March 2020

1 reference

High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing

31 March 2020

1 reference

Multiplex padlock targeted sequencing reveals human hypermutable CpG variations

31 March 2020

1 reference

Paired-end genomic signature tags: a method for the functional analysis of genomes and epigenomes.

31 March 2020

1 reference

Paired-end sequence mapping detects extensive genomic rearrangement and translocation during divergence of Francisella tularensis subsp. tularensis and Francisella tularensis subsp. holarctica populations

31 March 2020

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Paired-end mapping reveals extensive structural variation in the human genome

31 March 2020

1 reference

Analysis and accurate quantification of CpG methylation by MALDI mass spectrometry.

31 March 2020

1 reference

Cytosine methylation profiling of cancer cell lines.

31 March 2020

1 reference

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

31 March 2020

1 reference

Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation

31 March 2020

1 reference

Large-scale profiling of archival lymph nodes reveals pervasive remodeling of the follicular lymphoma methylome

31 March 2020

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Prevention of PCR cross-contamination by UNG treatment of bisulfite-treated DNA.

31 March 2020

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Control of carry-over contamination for PCR-based DNA methylation quantification using bisulfite treated DNA.

31 March 2020

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Substantial biases in ultra-short read data sets from high-throughput DNA sequencing

31 March 2020

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Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA.

31 March 2020

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31 March 2020

1 reference

Analysis of repetitive element DNA methylation by MethyLight

31 March 2020

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Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation

31 March 2020

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Copy number variation has little impact on bead-array-based measures of DNA methylation.

31 March 2020

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Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers

31 March 2020

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Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level

31 March 2020

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DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight

31 March 2020

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Sensitive digital quantification of DNA methylation in clinical samples

31 March 2020

1 reference

Single-molecule polymerase chain reaction reduces bias: application to DNA methylation analysis by bisulfite sequencing

31 March 2020

1 reference

Computational epigenetics

31 March 2020

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Research funding. Are epigeneticists ready for big science?

31 March 2020

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Moving AHEAD with an international human epigenome project.

31 March 2020

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Single-molecule sequencing of an individual human genome

31 March 2020

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Real-time DNA sequencing from single polymerase molecules

31 March 2020

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The potential and challenges of nanopore sequencing

31 March 2020

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Continuous base identification for single-molecule nanopore DNA sequencing

31 March 2020

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Feature selection for DNA methylation based cancer classification

31 March 2020

1 reference

Bisulfite sequencing Data Presentation and Compilation (BDPC) web server--a useful tool for DNA methylation analysis.

31 March 2020

1 reference

BSMAP: whole genome bisulfite sequence MAPping program

31 March 2020

1 reference

CpG analyzer, a Windows-based utility program for investigation of DNA methylation

31 March 2020

1 reference

CpGcluster: a distance-based algorithm for CpG-island detection

31 March 2020

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An evaluation of new criteria for CpG islands in the human genome as gene markers

31 March 2020

1 reference

CpG PatternFinder: a Windows-based utility program for easy and rapid identification of the CpG methylation status of DNA.

31 March 2020

1 reference

Large-scale human promoter mapping using CpG islands.

31 March 2020

1 reference

Sequence analysis and editing for bisulphite genomic sequencing projects

31 March 2020

1 reference

CyMATE: a new tool for methylation analysis of plant genomic DNA after bisulphite sequencing.

31 March 2020

1 reference

MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment.

31 March 2020

1 reference

methBLAST and methPrimerDB: web-tools for PCR based methylation analysis

31 March 2020

1 reference

MethDB--a public database for DNA methylation data

31 March 2020

1 reference

DNA Methylation Database "MethDB": a user guide.

31 March 2020

1 reference

An improved version of the DNA Methylation database (MethDB)

31 March 2020

1 reference

The MethDB DAS server: adding an epigenetic information layer to the human genome.

31 March 2020

1 reference

MethPrimer: designing primers for methylation PCRs

31 March 2020

1 reference

MethTools--a toolbox to visualize and analyze DNA methylation data

31 March 2020

1 reference

MethyCancer: the database of human DNA methylation and cancer

31 March 2020

1 reference

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

31 March 2020

1 reference

PubMeth: a cancer methylation database combining text-mining and expert annotation

31 March 2020

1 reference

QUMA: quantification tool for methylation analysis

31 March 2020

1 reference

Dissecting complex epigenetic alterations in breast cancer using CpG island microarrays.

31 March 2020

1 reference

12 December 2020

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification

1 reference

12 December 2020

CpG island arrays: an application toward deciphering epigenetic signatures of breast cancer

1 reference

12 December 2020

The CpG island searcher: a new WWW resource.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRG2732

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Dimensions Publication ID

31 July 2017

1026070037

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Fatcat ID

release_dwtbgplmzrdavint4synbvms3y

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Fatcat

https://api.fatcat.wiki/v0/release/dwtbgplmzrdavint4synbvms3y

24 November 2022

mapped directly with Wikidata item

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