(Q34094707)

31 July 2017

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title

Immune function of microglia (English)

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31 July 2017

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Aloisi F

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31 July 2017

publication date

1 November 2001

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

165-179

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Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy.

31 July 2017

cites work

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Brain microglia constitutively express beta-2 integrins

21 January 2018

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Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

21 January 2018

1 reference

21 January 2018

Glia-T cell dialogue.

1 reference

Impairment of TNF-receptor-1 signaling but not fas signaling diminishes T-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice

21 January 2018

1 reference

Surveillance, intervention and cytotoxicity: is there a protective role of microglia?

21 January 2018

1 reference

T-cell apoptosis in inflammatory brain lesions: destruction of T cells does not depend on antigen recognition

21 January 2018

1 reference

Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro

21 January 2018

1 reference

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier

21 January 2018

1 reference

NF-kappa B activation by tumor necrosis factor and interleukin-1.

21 January 2018

1 reference

Mature microglia resemble immature antigen-presenting cells

21 January 2018

1 reference

Tumor Necrosis Factor-α Mediates the Release of Bioactive Transforming Growth Factor-β in Murine Microglial Cell Cultures

21 January 2018

1 reference

Chemokines induce migration and changes in actin polymerization in adult rat brain microglia and a human fetal microglial cell line in vitro

21 January 2018

1 reference

Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new view

21 January 2018

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Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs

21 January 2018

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Interferon-gamma receptor-mediated but not tumor necrosis factor receptor type 1- or type 2-mediated signaling is crucial for the activation of cerebral blood vessel endothelial cells and microglia in murine Toxoplasma encephalitis

21 January 2018

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Expression of transforming growth factor (TGF)-beta1, -beta2, and -beta3 isoforms and TGF-beta type I and type II receptors in multiple sclerosis lesions and human adult astrocyte cultures

21 January 2018

1 reference

Extracellular human T-cell lymphotropic virus type I Tax protein induces cytokine production in adult human microglial cells

21 January 2018

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Human microglia activate lymphoproliferative responses to recall viral antigens

21 January 2018

1 reference

Direct ex vivo flow cytometric analysis of human microglial cell CD4 expression: examination of central nervous system biopsy specimens from HIV-seropositive patients and patients with other neurological disease

21 January 2018

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CR3: a general purpose adhesion-recognition receptor essential for innate immunity

21 January 2018

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IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

21 January 2018

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Cytokine responses induced by Toxoplasma gondii in astrocytes and microglial cells

21 January 2018

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Microglia induce CD4 T lymphocyte final effector function and death

21 January 2018

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Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells

21 January 2018

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Molecular mechanisms of microglial activation. A. Implications for regeneration and neurodegenerative diseases

21 January 2018

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Microglia: Intrinsic immuneffector cell of the brain

21 January 2018

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CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis

21 January 2018

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Other functions, other genes: alternative activation of antigen-presenting cells

21 January 2018

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Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis

21 January 2018

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Transcription factor NF-kappaB and inhibitor I kappaBalpha are localized in macrophages in active multiple sclerosis lesions

21 January 2018

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Mouse brain microglia express interleukin-15 and its multimeric receptor complex functionally coupled to Janus kinase activity

21 January 2018

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Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

21 January 2018

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Microglia are the major cell type expressing MHC class II in human white matter

21 January 2018

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A Toll-like receptor recognizes bacterial DNA

21 January 2018

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Modulation of interleukin-1 and tumor necrosis factor expression by ?-adrenergic agonists in mouse ameboid microglial cells

21 January 2018

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Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia

21 January 2018

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Down-regulation of the macrophage lineage through interaction with OX2 (CD200)

21 January 2018

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Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice

21 January 2018

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Role of CD14 in cellular recognition of bacterial lipopolysaccharides

21 January 2018

2 references

21 January 2018

7 January 2021

Interaction between apoptotic cells and reactive brain cells in the central nervous system of rats with autoimmune encephalomyelitis

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The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis

21 January 2018

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CD95's deadly mission in the immune system

21 January 2018

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Cervical lymphoid tissue but not the central nervous system supports proliferation of virus-specific T lymphocytes during coronavirus-induced encephalitis in rats

21 January 2018

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Bone marrow derived elements and resident microglia in brain inflammation

21 January 2018

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Adhesion molecule expression and regulation on cells of the central nervous system

21 January 2018

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Regulation of prostanoid synthesis in microglial cells and effects of prostaglandin E2 on microglial functions

21 January 2018

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Mannose receptor and its putative ligands in normal murine lymphoid and nonlymphoid organs: In situ expression of mannose receptor by selected macrophages, endothelial cells, perivascular microglia, and mesangial cells, but not dendritic cells

21 January 2018

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Macrophage lectins in host defence

21 January 2018

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Role of dendritic cells in the induction and maintenance of autoimmune diseases

21 January 2018

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Regulation of inhibitory pathways of the interleukin-1 system

21 January 2018

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Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells

21 January 2018

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Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes

21 January 2018

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Chemokine and chemokine-receptor expression in human glial elements: induction by the HIV protein, Tat, and chemokine autoregulation

21 January 2018

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Innate immune recognition: mechanisms and pathways

21 January 2018

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Cytokines in inflammatory brain lesions: helpful and harmful

21 January 2018

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Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide

21 January 2018

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The expanding universe of T-cell subsets: Th1, Th2 and more.

21 January 2018

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Complement anaphylatoxin receptors on neurons: new tricks for old receptors?

21 January 2018

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Neuronal control of MHC class II inducibility in rat astrocytes and microglia

21 January 2018

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Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor

21 January 2018

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Inflammation and Alzheimer's disease

21 January 2018

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IL-4-activated STAT-6 inhibits IFN-gamma-induced CD40 gene expression in macrophages/microglia

21 January 2018

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Cytokines induce the development of functionally heterogeneous T helper cell subsets

21 January 2018

1 reference

Class II transactivator and class II MHC gene expression in microglia: modulation by the cytokines TGF-beta, IL-4, IL-13 and IL-10.

21 January 2018

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Critical Influences of the Cytokine Orchestration on the Outcome of Myelin Antigen‐Specific T‐Cell Autoimmunity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

21 January 2018

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Apoptosis of inflammatory cells in immune control of the nervous system: role of glia

21 January 2018

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Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease

21 January 2018

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A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation

21 January 2018

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Local neurochemicals and site-specific immune regulation in the CNS.

21 January 2018

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Murine microglial cells produce and respond to interleukin-18.

21 January 2018

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Microglial activation by components of gram-positive and -negative bacteria: distinct and common routes to the induction of ion channels and cytokines.

21 January 2018

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The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases

21 January 2018

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Upregulation of COX-2 and CGRP expression in resident cells of the Borna disease virus-infected brain is dependent upon inflammation

21 January 2018

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Corpse clearance defines the meaning of cell death

21 January 2018

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Transient in vivo activation of rat brain macrophages/microglial cells and astrocytes by immunostimulatory multiple CpG oligonucleotides

21 January 2018

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Tumor necrosis factor: a master-regulator of leukocyte movement

21 January 2018

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CD28/CTLA-4 and CD80/CD86 families: signaling and function

21 January 2018

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Macrophage and microglial responses to cytokines in vitro: phagocytic activity, proteolytic enzyme release, and free radical production

21 January 2018

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Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

21 January 2018

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The role of microglia and macrophages in the pathophysiology of the CNS.

21 January 2018

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21 January 2018

Reactive microgliosis

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Production of interleukin-12 and expression of its receptors by murine microglia

21 January 2018

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Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

21 January 2018

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Reactive microglia in multiple sclerosis lesions have an increased expression of receptors for the Fc part of IgG.

21 January 2018

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Macrophage phagocytosis of myelin in vitro determined by flow cytometry: phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide

21 January 2018

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Activation of adult human derived microglia by myelin phagocytosis in vitro

21 January 2018

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Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system

21 January 2018

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Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

21 January 2018

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Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition.

21 January 2018

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Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function

21 January 2018

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Anti-inflammatory effects of prostaglandin E2 in the central nervous system in response to brain injury and circulating lipopolysaccharide

21 January 2018

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Chemokines: a new classification system and their role in immunity

21 January 2018

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Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells

21 January 2018

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7 January 2021

Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS

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7 January 2021

Cytokine actions in the central nervous system

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7 January 2021

Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions

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7 January 2021

The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia

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7 January 2021

The adhesion molecule and cytokine profile of multiple sclerosis lesions

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7 January 2021

Microglial cells qualify as the stimulators of unprimed CD4+ and CD8+ T lymphocytes in the central nervous system

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7 January 2021

Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines

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7 January 2021

Induction of superoxide anion and nitric oxide production in cultured microglia.

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7 January 2021

The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions.

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7 January 2021

Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia

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7 January 2021

Neuronal FasL induces cell death of encephalitogenic T lymphocytes

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7 January 2021

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

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7 January 2021

Central nervous system delivery of interleukin 4 by a nonreplicative herpes simplex type 1 viral vector ameliorates autoimmune demyelination

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7 January 2021

Both adenosine A1- and A2-receptors are required to stimulate microglial proliferation

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7 January 2021

Chemokines and chemokine receptors in CNS pathology.

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7 January 2021

Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice

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7 January 2021

Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β

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7 January 2021

Transcription factor NF-kappa B is activated in microglia during experimental autoimmune encephalomyelitis

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7 January 2021

Sequential expression of transforming growth factor-beta1 by T-cells, macrophages, and microglia in rat spinal cord during autoimmune inflammation

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7 January 2021

Coexpression of Fas/FasL and Bax on brain and infiltrating T cells in the central nervous system is closely associated with apoptotic cell death during autoimmune encephalomyelitis

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7 January 2021

Microglia-derived macrophages in early multiple sclerosis plaques

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7 January 2021

Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats

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7 January 2021

Microglia induce myelin basic protein-specific T cell anergy or T cell activation, according to their state of activation

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7 January 2021

Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells

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7 January 2021

Receptor-mediated phagocytosis of myelin by macrophages and microglia: effect of opsonization and receptor blocking agents

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7 January 2021

Involvement of STAT-1 and ets family members in interferon-gamma induction of CD40 transcription in microglia/macrophages

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7 January 2021

The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense

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7 January 2021

Astrocyte-targeted expression of IL-12 induces active cellular immune responses in the central nervous system and modulates experimental allergic encephalomyelitis.

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7 January 2021

Protein kinase C activation reduces microglial cyclic AMP response to prostaglandin E2 by interfering with EP2 receptors

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7 January 2021

Differential production of and migratory response to beta chemokines by human microglia and astrocytes

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7 January 2021

IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells

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7 January 2021

Expression of the beta-chemokine receptors CCR2, CCR3 and CCR5 in multiple sclerosis central nervous system tissue

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7 January 2021

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

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7 January 2021

Brain macrophages: on the role of pericytes and perivascular cells

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7 January 2021

Differential expression of MHC class II molecules by microglia and neoplastic astroglia: relevance for the escape of astrocytoma cells from immune surveillance

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7 January 2021

Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: a role for transforming growth factor beta

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7 January 2021

Cyclooxygenase-2 is highly expressed in microglial-like cells in a murine model of prion disease

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7 January 2021

Neurotrophins and the anti-inflammatory agents interleukin-4 (IL-4), IL-10, IL-11 and transforming growth factor-beta1 (TGF-beta1) down-regulate T cell costimulatory molecules B7 and CD40 on cultured rat microglia

1 reference

7 January 2021

The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis

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7 January 2021

Identifiers

DOI

10.1002/GLIA.1106

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31 July 2017

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