(Q34085901)

30 July 2017

title

MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output (English)

1 reference

30 July 2017

author

Jean-Christophe Marine

object named as

Jean-Christophe Marine

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Thomas Jenuwein

1 reference

30 July 2017

Lihong Chen

1 reference

30 July 2017

Zhenyu Li

1 reference

30 July 2017

Aleksandra K Zwolinska

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30 July 2017

Matthew A Smith

1 reference

30 July 2017

Brittany Cross

1 reference

30 July 2017

John Koomen

1 reference

30 July 2017

Zhi-Min Yuan

1 reference

30 July 2017

Kenneth L Wright

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30 July 2017

Jiandong Chen

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30 July 2017

language of work or name

English

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publication date

29 June 2010

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

2538-2552

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2928696/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

G9a and Glp methylate lysine 373 in the tumor suppressor p53

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Arginine methylation regulates the p53 response

5 July 2018

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p53 is regulated by the lysine demethylase LSD1

5 July 2018

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Modulation of p53 function by SET8-mediated methylation at lysine 382

5 July 2018

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5 July 2018

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Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network

5 July 2018

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Mouse double minute 2 associates with chromatin in the presence of p53 and is released to facilitate activation of transcription

5 July 2018

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Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo

5 July 2018

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5 July 2018

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The diverse functions of histone lysine methylation

5 July 2018

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MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation

5 July 2018

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Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

5 July 2018

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Regulation of p53-MDMX interaction by casein kinase 1 alpha

5 July 2018

1 reference

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A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells

5 July 2018

1 reference

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Mdmx as an essential regulator of p53 activity

5 July 2018

1 reference

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5 July 2018

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Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

5 July 2018

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The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression.

5 July 2018

1 reference

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Regulation of p53 activity through lysine methylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Inhibition of HDM2 and activation of p53 by ribosomal protein L23

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Yin Yang 1 is a negative regulator of p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation

5 July 2018

1 reference

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

MDM2 promotes ubiquitination and degradation of MDMX

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Regulation of HDM2 activity by the ribosomal protein L11

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Critical contribution of the MDM2 acidic domain to p53 ubiquitination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Rb targets histone H3 methylation and HP1 to promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Control of p53 ubiquitination and nuclear export by MDM2 and ARF.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Regulation of chromatin structure by site-specific histone H3 methyltransferases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Repression of p53-mediated transcription by MDM2: a dual mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

MDMX: a novel p53-binding protein with some functional properties of MDM2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Mapping of the p53 and mdm-2 Interaction Domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928696

Mechanistic insights into maintenance of high p53 acetylation by PTEN.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.140

Distinct roles of Mdm2 and Mdm4 in red cell production

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.140

MDM2 and MDMX can interact differently with ARF and members of the p53 family

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.140

21 January 2018

Identifiers

DOI

10.1038/EMBOJ.2010.140

1 reference

30 July 2017

1 reference

30 July 2017

1 reference