(Q34073891)

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Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients

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Europe PubMed Central

PubMed publication ID

30 July 2017

Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

Angus W. Thomson

8

object named as

Angus W Thomson

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Giorgio Raimondi

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Tina L Sumpter

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Benjamin M Matta

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Mahesh Pillai

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Natasha Corbitt

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Yoram Vodovotz

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Zhiliang Wang

7

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

9 December 2009

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Journal of Immunology

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Europe PubMed Central

PubMed publication ID

30 July 2017

184

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

624-636

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

1 reference

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5 July 2018

Immunoregulatory functions of mTOR inhibition.

1 reference

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5 July 2018

Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Regulatory T cells overturned: the effectors fight back

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Antigen-specific peripheral shaping of the natural regulatory T cell population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

1 reference

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5 July 2018

Toll-like receptor signaling in transplantation

1 reference

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5 July 2018

Regulatory T cells: hypes and limitations.

1 reference

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5 July 2018

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Induction and effector functions of T(H)17 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Regulatory T cells and immune tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

IL-13-mediated gender difference in susceptibility to autoimmune encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Tolerogenic dendritic cells and the quest for transplant tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

CD4+CD25+ regulatory T cells in transplantation: progress, challenges and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Foxp3 in control of the regulatory T cell lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Naturally occurring regulatory T cells: recent insights in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

IL-17 family cytokines and the expanding diversity of effector T cell lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Immune privilege induced by regulatory T cells in transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

T regulatory cells and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Patients, pathogens, and protective immunity: the relevance of virus-induced alloreactivity in transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Antigen-specific regulatory T cells--ex vivo expansion and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Organ transplantation--how much of the promise has been realized?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Role of LAG-3 in regulatory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Regulatory T cells in transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

The complementary roles of deletion and regulation in transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

CD4+ CD25+ suppressor T cells: more questions than answers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Identification of regulatory T cells in tolerated allografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

5 July 2018

Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Critical role of IL-2 and TGF-beta in generation, function and stabilization of Foxp3+CD4+ Treg.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Cutting edge: size and diversity of CD4+CD25high Foxp3+ regulatory T cell repertoire in humans: evidence for similarities and partial overlapping with CD4+CD25- T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Regulatory T cell development in the absence of functional Foxp3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

The IL-4 receptor alpha-chain-binding cytokines, IL-4 and IL-13, induce forkhead box P3-expressing CD25+CD4+ regulatory T cells from CD25-CD4+ precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Regulatory T-cell therapy: is it ready for the clinic?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Toll-dependent control mechanisms of CD4 T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923839

28 October 2018

Induction of peripheral T cell tolerance by antigen-presenting B cells. II. Chronic antigen presentation overrules antigen-presenting B cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of CD4+ CD25+ regulatory T cell suppressor function by analogs of the selecting peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation and expansion of human CD4+ CD25+ regulatory T cells with indirect allospecificity: Potential reagents to promote donor-specific transplantation tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cells dynamically control the primary immune response to foreign antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ex vivo-expanded natural CD4+CD25+ regulatory T cells synergize with host T-cell depletion to promote long-term survival of allografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasticity of regulatory T cells: subversion of suppressive function and conversion to enhancement of lung allergic responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-regulatory cells in human transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory tolerance-mediating T cells in transplantation tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cell subsets in blood and lymphoid tissue of rhesus monkeys and their mobilization with Flt3 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPLIFICATION OF NATURAL REGULATORY IMMUNE MECHANISMS FOR TRANSPLANTATION TOLERANCE1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of peripheral T cell tolerance by antigen-presenting B cells. I. Relevance of antigen presentation persistence

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0900936

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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