(Q34066446)

30 July 2017

1 reference

title

The role of NF-AT transcription factors in T cell activation and differentiation (English)

1 reference

30 July 2017

1 reference

E Serfling

1 reference

30 July 2017

F Berberich-Siebelt

1 reference

30 July 2017

S Chuvpilo

1 reference

30 July 2017

E Jankevics

1 reference

30 July 2017

S Klein-Hessling

1 reference

30 July 2017

T Twardzik

1 reference

30 July 2017

A Avots

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 October 2000

1 reference

Biochimica et Biophysica Acta

30 July 2017

published in

1 reference

30 July 2017

volume

1498

1 reference

30 July 2017

1 reference

30 July 2017

page(s)

1-18

1 reference

Identification of a putative regulator of early T cell activation genes

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

FK506 and cyclosporin, molecular probes for studying intracellular signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Mechanisms of transactivation by nuclear factor of activated T cells-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

CBP/p300 Integrates Raf/Rac-Signaling Pathways in the Transcriptional Induction of NF-ATc during T Cell Activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Rapid targeting of nuclear proteins to the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATc

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Expression of NFAT-family proteins in normal human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Control of NFATx1 nuclear translocation by a calcineurin-regulated inhibitory domain

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

NF-AT components define a family of transcription factors targeted in T-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Solution structure of the core NFATC1/DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Recognition of NFATp/AP-1 composite elements within genes induced upon the activation of immune cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Transcriptional regulation of the IL-2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The architecture of the interleukin-2 promoter: a reflection of T lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

An enhanced immune response in mice lacking the transcription factor NFAT1.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

NF-ATp plays a prominent role in the transcriptional induction of Th2-type lymphokines

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Role of nuclear factor of activated T cells (NFAT) in the expression of interleukin-5 and other cytokines involved in the regulation of hemopoetic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Definition of cis-regulatory elements of the mouse interleukin-5 gene promoter. Involvement of nuclear factor of activated T cell-related factors in interleukin-5 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Activation of the Interleukin-5 Promoter by cAMP in Murine EL-4 Cells Requires the GATA-3 and CLE0 Elements

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Nuclear factor of activated T cells and YY1 combine to repress IL-5 expression in a human T-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Interaction of NF-kappaB and NFAT with the interferon-gamma promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

A T cell-specific enhancer in the interleukin-3 locus is activated cooperatively by Oct and NFAT elements within a DNase I-hypersensitive site

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The interleukin 2 receptor alpha chain/CD25 promoter is a target for nuclear factor of activated T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Two NFAT Transcription Factor Binding Sites Participate in the Regulation of CD95 (Fas) Ligand Expression in Activated Human T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Sequential involvement of NFAT and Egr transcription factors in FasL regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The CD40L promoter contains nuclear factor of activated T cells-binding motifs which require AP-1 binding for activation of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Regulation of transcription by MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

FKBP12 Binds the Inositol 1,4,5-Trisphosphate Receptor at Leucine-Proline (1400–1401) and Anchors Calcineurin to this FK506-like Domain

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Transcription factors of the NFAT family: regulation and function

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Interaction of calcineurin with a domain of the transcription factor NFAT1 that controls nuclear import

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp)

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Manipulating immune responses with immunosuppressive agents that target NFAT.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Identification of amino acid residues and protein kinases involved in the regulation of NFATc subcellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Nuclear Accumulation of NFAT4 Opposed by the JNK Signal Transduction Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Defective T Cell Differentiation in the Absence of Jnk1

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Nucleocytoplasmic transport: the last 200 nanometers

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Modification by nuclear export?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP)

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Co-activators and co-repressors in the integration of transcriptional responses

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Coupling RNA polymerase II transcription with pre-mRNA processing

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Cytokines induce the development of functionally heterogeneous T helper cell subsets

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Multistage regulation of Th1-type immune responses by the transcription factor IRF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

NF-AT-Driven interleukin-4 transcription potentiated by NIP45

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The transcription factor NF-ATc is essential for cardiac valve formation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Requirement for transcription factor NFAT in interleukin-2 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guérin (BCG) suppresses allergen-induced airway eosinophilia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Retarded thymic involution and massive germinal center formation in NF-ATp-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The transcription factor NFAT4 is involved in the generation and survival of T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

C/EBPbeta enhances IL-4 but impairs IL-2 and IFN-gamma induction in T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2800%2900082-3

7 January 2021

10.1016/S0167-4889(00)00082-3

Identifiers

DOI

1 reference

30 July 2017

1 reference