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Cyclic nucleotide phosphodiesterases: relating structure and function

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Europe PubMed Central

PubMed publication ID

30 July 2017

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Europe PubMed Central

Cyclic nucleotide phosphodiesterases: relating structure and function (English)

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Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Francis SH

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Turko IV

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Corbin JD

3

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Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

1 January 2001

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Europe PubMed Central

PubMed publication ID

30 July 2017

Progress in Molecular Biology and Translational Science

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Europe PubMed Central

PubMed publication ID

30 July 2017

65

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Europe PubMed Central

PubMed publication ID

30 July 2017

1-52

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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Hormonal regulation of cyclic nucleotide phosphodiesterases

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Signal transduction enzymes of vertebrate photoreceptors

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Type III cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE3 gene family)

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Diversity in cyclic nucleotide phosphodiesterase isoenzyme families

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Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

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Cyclic nucleotide phosphodiesterases and vascular smooth muscle

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Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3)

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Tailoring cAMP-signalling responses through isoform multiplicity

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Phosphorylation and activation of hormone-sensitive adipocyte phosphodiesterase type 3B.

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Ancient gene duplication and domain shuffling in the animal cyclic nucleotide phosphodiesterase family

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Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase

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Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases

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Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain

1 reference

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Sequence comparison of the 63-, 61-, and 59-kDa calmodulin-dependent cyclic nucleotide phosphodiesterases

1 reference

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Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase

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Expression of an active, monomeric catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase (PDE5)

1 reference

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Three new potential cAMP affinity labels. Inactivation of human platelet low Km cAMP phosphodiesterase by 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic monophosphate

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A photoaffinity probe covalently modifies the catalytic site of the cGMP-binding cGMP-specific phosphodiesterase (PDE-5).

1 reference

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Critical role of conserved histidine pairs HNXXH and HDXXH in recombinant human phosphodiesterase 4A

1 reference

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Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase.

1 reference

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Hydrolysis of cyclic nucleotides by a purified cGMP-stimulated phosphodiesterase: structural requirements for hydrolysis

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A stereochemical investigation of the hydrolysis of cyclic AMP and the (Sp)-and (Rp)-diastereoisomers of adenosine cyclic 3′:5′-phosphorothioate by bovine heart and baker's-yeast cyclic AMP phosphodiesterases

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Characterization of phosphodiesterase catalytic sites by means of cyclic nucleotide derivatives

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Hydropathic analysis and mutagenesis of the catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase (PDE5). cGMP versus cAMP substrate selectivity

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Expression and mutagenesis of the catalytic domain of cGMP-inhibited phosphodiesterase (PDE3) cloned from human platelets

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Interaction of the catalytic subunit of protein kinase A with the lung type V cyclic GMP phosphodiesterase: modulation of non-catalytic binding sites

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Proposal for Pharmacologically Distinct Conformers of PDE4 Cyclic AMP Phosphodiesterases

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Role of conserved histidines in catalytic activity and inhibitor binding of human recombinant phosphodiesterase 4A

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Identification of inhibitor specificity determinants in a mammalian phosphodiesterase

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New perspective on zinc biochemistry: cocatalytic sites in multi-zinc enzymes

1 reference

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Research requires action

1 reference

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Histidine-607 and histidine-643 provide important interactions for metal support of catalysis in phosphodiesterase-5

1 reference

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based on heuristic

inferred from DOI database lookup

Zinc Dependent Activation of cAMP-Specific Phosphodiesterase (PDE4A)

1 reference

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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1 reference

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based on heuristic

inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

Structure of thermolysin refined at 1.6 A resolution

1 reference

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1 reference

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1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

PDE isoenzymes as targets for anti-asthma drugs

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphodiesterase isozymes: molecular targets for novel antiasthma agents

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Leptin inhibits insulin secretion by activation of phosphodiesterase 3B.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of cellular responses by hormones: role of cAMP specific, rolipram-sensitive phosphodiesterases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs)

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of cyclic GMP-inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: differential subcellular localization and regulated expression by cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual regulation of heat-stable enterotoxin-mediated cGMP accumulation in T84 cells by receptor desensitization and increased phosphodiesterase activity

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental changes in lung cGMP phosphodiesterase-5 activity, protein, and message

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

CD3- and CD28-dependent induction of PDE7 required for T cell activation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: 'designer' changes in Vmax, stability and membrane association.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Compartmentalization of cyclic AMP phosphodiesterases, signalling 'crosstalk', desensitization and the phosphorylation of Gi-2 add cell specific personalization to the control of the levels of the second messenger cyclic AMP.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4. Regulation of superoxidation and mitogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular localization of rolipram-sensitive, cAMP-specific phosphodiesterases. Differential targeting and activation of the splicing variants derived from the PDE4D gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of a calmodulin-dependent phosphodiesterase isoform (PDE1B1) correlates with brain regions having extensive dopaminergic innervation.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Precision substrate targeting of protein kinases. The cGMP- and cAMP-dependent protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic structure and chromosome location of the murine PDE1B phosphodiesterase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a Ca2+-calmodulin-stimulated cyclic GMP phosphodiesterase from bovine brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a calmodulin-dependent high-affinity cyclic AMP and cyclic GMP phosphodiesterase from male mouse germ cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic nucleotide phosphodiesterases in somatic and germ cells of mouse seminiferous tubules

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine eye: high calmodulin affinity isozyme immunologically related to the brain 60-kDa isozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of inhibitory and calmodulin-binding domains of the PDE1A1 and PDE1A2 calmodulin-stimulated cyclic nucleotide phosphodiesterases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation and characterization of bovine heart calmodulin-dependent phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of the 61-kDa calmodulin-stimulated cyclic nucleotide phosphodiesterase at serine 120 reduces its affinity for calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Crosslinking of iodine-125-labeled calcium-dependent regulatory protein to the calcium(2+) ion-sensitive phosphodiesterase purified from bovine heart

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium modulates the rapid kinetics of the odorant-induced cyclic AMP signal in rat olfactory cilia.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium controls second-messenger signalling in olfactory cilia

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and properties of cyclic nucleotide phosphodiesterases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification and partial characterization of membrane-associated type II (cGMP-activatable) cyclic nucleotide phosphodiesterase from rabbit brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amino acid sequence of the cyclic GMP stimulated cyclic nucleotide phosphodiesterase from bovine heart

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3′,5′-cyclic nucleotide phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Paradoxical stimulation by 1-methyl-3-isobutylxanthine of rat liver cyclic AMP phosphodiesterase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic nucleotide analogs used to study phosphodiesterase catalytic and allosteric sites

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Specificity of cGMP binding to a purified cGMP-stimulated phosphodiesterase from bovine adrenal tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The domain structure of the calmodulin-dependent phosphodiesterase isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of cGMP-stimulated phosphodiesterase by nitroprusside limits cAMP accumulation in human platelets: effects on platelet aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of cyclic GMP and cyclic AMP during neutrophil migration: involvement of phosphodiesterase type III

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Single-step affinity purification, partial structure and properties of human platelet cGMP inhibited cAMP phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The cGMP-inhibitable phosphodiesterase modulates glucose transport activation by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular localization and biological function of specific cyclic nucleotide phosphodiesterases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the cDNA and gene encoding human PDE3B, the cGIP1 isoform of the human cyclic GMP-inhibited cyclic nucleotide phosphodiesterase family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of the site in the cGMP-inhibited phosphodiesterase phosphorylated in adipocytes in response to insulin and isoproterenol

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin induced phosphorylation and activation of the cGMP-inhibited cAMP phosphodiesterase in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Stimulation by Insulin of a Serine Kinase in Human Platelets That Phosphorylates and Activates the cGMP-Inhibited cAMP Phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: a diverse family of regulatory enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning of a novel splice variant of human type IVA (PDE-IVA) cyclic AMP phosphodiesterase and localization of the gene to the p13.2-q12 region of human chromosome 19 [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and expression, in both COS-1 cells and S. cerevisiae, of a human cytosolic type-IVA, cyclic AMP specific phosphodiesterase (hPDE-IVA-h6.1)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of cyclic AMP-phosphodiesterase variants from the PDE4D gene expressed in human peripheral mononuclear cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts. Characterization of a novel tissue-specific isoform, RNPDE4A8.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple splice variants of phosphodiesterase PDE4C cloned from human lung and testis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular distribution of high-affinity type IV cyclic AMP phosphodiesterase activity in rabbit ventricular myocardium: relations to the effects of cardiotonic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Chimeric constructs show that the unique N-terminal domain of the cyclic AMP phosphodiesterase RD1 (RNPDE4A1A; rPDE-IVA1) can confer membrane association upon the normally cytosolic protein chloramphenicol acetyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective activation of rolipram-sensitive, cAMP-specific phosphodiesterase isoforms by phosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinant expression of a type IV, cAMP-specific phosphodiesterase: characterization and structure-function studies of deletion mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of PDE-4 cAMP phosphodiesterases by phosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Engineered deletion of the unique N-terminal domain of the cyclic AMP-specific phosphodiesterase RD1 prevents plasma membrane association and the attainment of enhanced thermostability without altering its sensitivity to inhibition by rolipram

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular compartmentalization of PDE4 cyclic AMP-specific phosphodiesterases.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the structure of the N-terminal splice region of the cyclic AMP-specific phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and identification of the membrane association domain using chimeric constructs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Human phosphodiesterase 4A: characterization of full-length and truncated enzymes expressed in COS cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Detailed characterization of a purified type 4 phosphodiesterase, HSPDE4B2B: differentiation of high- and low-affinity (R)-rolipram binding

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a hormone-inducible, high affinity adenosine 3'-5'-cyclic monophosphate phosphodiesterase from the rat Sertoli cell

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic GMP phosphodiesterase-5: target of sildenafil

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel alternative splice variants of cGMP-binding cGMP-specific phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of three isoforms of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in human penile cavernosum

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression, structure and chromosomal localization of the human cGMP-binding cGMP-specific phosphodiesterase PDE5A gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic origin and transcriptional regulation of two variants of cGMP-binding cGMP-specific phosphodiesterases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The Regulation of the cGMP-binding cGMP Phosphodiesterase by Proteins That Are Immunologically Related to γ Subunit of the Photoreceptor cGMP Phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Studies of the molecular mechanism of discrimination between cGMP and cAMP in the allosteric sites of the cGMP-binding cGMP-specific phosphodiesterase (PDE5)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

An essential aspartic acid at each of two allosteric cGMP-binding sites of a cGMP-specific phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of key amino acids in a conserved cGMP-binding site of cGMP-binding phosphodiesterases. A putative NKXnD motif for cGMP binding

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanism of visual transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic GMP phosphodiesterase from bovine retina. Amino acid sequence of the alpha-subunit and nucleotide sequence of the corresponding cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Subunit structure of rod cGMP-phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Affinities of bovine photoreceptor cGMP phosphodiesterases for rod and cone inhibitory subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and characterization of the G protein gamma subunit of cone photoreceptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of human and mouse rod cGMP phosphodiesterase delta subunit (PDE6D) and chromosomal localization of the human gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural features of the noncatalytic cGMP binding sites of frog photoreceptor phosphodiesterase using cGMP analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Role for the target enzyme in deactivation of photoreceptor G protein in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific interaction of topoisomerase II beta and the CD3 epsilon chain of the T cell receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Two-site high-affinity interaction between inhibitory and catalytic subunits of rod cyclic GMP phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The gamma subunit of rod cGMP-phosphodiesterase blocks the enzyme catalytic site

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of phosphodiesterase by transducin in bovine rod outer segments: characteristics of the successive binding of two transducins.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction between the retinal cyclic GMP phosphodiesterase inhibitor and transducin. Kinetics and affinity studies

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Interactions of a G-protein with its effector: transducin and cGMP phosphodiesterase in retinal rods

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The carboxyl terminus of the gamma-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the alpha-subunit of transducin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of allosteric regulation of the rod cGMP phosphodiesterase activity by the helical domain of transducin alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Onset of Feedback Reactions Underlying Vertebrate Rod Photoreceptor Light Adaptation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

RGS9, a GTPase accelerator for phototransduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Active sites of the cyclic GMP phosphodiesterase gamma-subunit of retinal rod outer segments

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Probing functional interfaces of rod PDE gamma-subunit using scanning fluorescent labeling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of transducin guanosine triphosphatase by two proteins of the RGS family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The retinal specific protein RGS-r competes with the gamma subunit of cGMP phosphodiesterase for the alpha subunit of transducin and facilitates signal termination

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

An interface of interaction between photoreceptor cGMP phosphodiesterase catalytic subunits and inhibitory gamma subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Residues within the polycationic region of cGMP phosphodiesterase gamma subunit crucial for the interaction with transducin alpha subunit. Identification by endogenous ADP-ribosylation and site-directed mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of GTP/T alpha-dependent activation of cGMP phosphodiesterase by ADP-ribosylation by its gamma subunit in amphibian rod photoreceptor membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of the gamma subunit of the retinal photoreceptor cGMP phosphodiesterase by the cAMP-dependent protein kinase and its effect on the gamma subunit interaction with other proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of Transducin GTPase Activity by Human Retinal RGS

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A possible role of RGS9 in phototransduction. A bridge between the cGMP-phosphodiesterase system and the guanylyl cyclase system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical analysis of the transducin-phosphodiesterase interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Coupling of muscarinic cholinergic receptors and cGMP in nocturnal regulation of the suprachiasmatic circadian clock

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alternative splicing of the high affinity cAMP-specific phosphodiesterase (PDE7A) mRNA in human skeletal muscle and heart

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of human PDE7B, a cAMP-specific phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation and characterization of PDE10A, a novel human 3', 5'-cyclic nucleotide phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Striatum- and testis-specific phosphodiesterase PDE10A isolation and characterization of a rat PDE10A

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization and phosphorylation of PDE10A2, a novel alternative splice variant of human phosphodiesterase that hydrolyzes cAMP and cGMP.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic nucleotide phosphodiesterases: gene complexity, regulation by phosphorylation, and physiological implications

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms involved in the antilipolytic action of insulin: phosphorylation and activation of a particulate adipocyte cAMP phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2965001-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0079-6603(00)65001-8

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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