(Q33965304)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

corrigendum / erratum

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Juliet A Williams

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Oivin M Guicherit

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Beatrice I Zaharian

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Yin Xu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Ling Chai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Hynek Wichterle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Charlene Kon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Christine Gatchalian

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Jeffery A Porter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Frank Y Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

4 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

2 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

4616-4621

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

2 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Small molecule modulation of Smoothened activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

TGF-beta signaling: positive and negative effects on tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Hedgehog signaling in animal development: paradigms and principles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

The Hedgehog and Wnt signalling pathways in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Enhanced potency of human Sonic hedgehog by hydrophobic modification.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Hedgehog signalling in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Linking colorectal cancer to Wnt signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Basal cell carcinomas in mice overexpressing Gli2 in skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Sonic hedgehog opposes epithelial cell cycle arrest

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Activating Smoothened mutations in sporadic basal-cell carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Basal cell carcinomas in mice overexpressing sonic hedgehog

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Sporadic medulloblastomas contain PTCH mutations.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Sertoli cell signaling by Desert hedgehog regulates the male germline

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Relationship between sunlight exposure and a key genetic alteration in basal cell carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Nevoid basal-cell carcinoma syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

Biology of basal cell carcinoma (Part I).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0732813100

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0732813100

Teratogen-mediated inhibition of target tissue response to Shh signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0732813100

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0732813100

The Hedgehog signalling pathway and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0732813100

Nonmelanoma skin cancer in the United States: incidence.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153604

29 October 2018

Identifiers

DOI

10.1073/PNAS.0732813100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

12679522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522%20AND%20SRC:MED&resulttype=core&format=json