(Q33830135)

29 July 2017

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title

A model for the cytoplasmic trafficking of signalling proteins involving the hsp90-binding immunophilins and p50cdc37. (English)

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29 July 2017

Pratt WB

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29 July 2017

Silverstein AM

series ordinal

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29 July 2017

Galigniana MD

series ordinal

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29 July 2017

publication date

1 December 1999

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29 July 2017

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inferred from page(s)

published in

Cellular Signalling

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

839-851

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Nucleocytoplasmic transport: the soluble phase

29 July 2017

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7 January 2021

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7 January 2021

Cytoplasmic-nuclear trafficking of steroid hormone receptors

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Nuclear localization of unoccupied oestrogen receptors

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Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

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7 January 2021

Immunocytochemical study of mammalian progesterone receptor using monoclonal antibodies

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7 January 2021

Ultrastructural localization of the progesterone receptor by an immunogold method: effect of hormone administration

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7 January 2021

v-mos oncoproteins affect the nuclear retention and reutilization of glucocorticoid receptors

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7 January 2021

Differential intracellular localization of human mineralocorticosteroid receptor on binding of agonists and antagonists

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7 January 2021

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

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7 January 2021

Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen

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7 January 2021

Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor

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7 January 2021

Evidence for colocalization of glucocorticoid receptor with cytoplasmic microtubules in human gingival fibroblasts, using two different monoclonal anti-GR antibodies, confocal laser scanning microscopy and image analysis

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7 January 2021

Immunocytology with microwave-fixed fibroblasts shows 1 alpha,25-dihydroxyvitamin D3-dependent rapid and estrogen-dependent slow reorganization of vitamin D receptors

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7 January 2021

Subcellular distribution of the glucocorticoid receptor and evidence for its association with microtubules

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7 January 2021

Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera

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7 January 2021

The cytoskeleton and the cellular traffic of the progesterone receptor

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7 January 2021

Microtubules are not required for glucocorticoid receptor mediated gene induction

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7 January 2021

Hsp90 & Co. - a holding for folding

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7 January 2021

Yeast molecular chaperones and the mechanism of steroid hormone action

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7 January 2021

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

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7 January 2021

The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain

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7 January 2021

Cyclophilin-40: evidence for a dimeric complex with hsp90.

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7 January 2021

Cyclophilin 40 (CyP-40), mapping of its hsp90 binding domain and evidence that FKBP52 competes with CyP-40 for hsp90 binding

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7 January 2021

Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

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7 January 2021

Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes

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https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor

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https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin

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https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins

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https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein

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7 January 2021

Association of the Transforming Proteins of Rous, Fujinami, and Y73 Avian Sarcoma Viruses with the Same Two Cellular Proteins

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7 January 2021

Association of the heat shock protein hsp90 with steroid hormone receptors and tyrosine kinase oncogene products

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7 January 2021

Association of Hsp90 with cellular Src-family kinases in a cell-free system correlates with altered kinase structure and function

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7 January 2021

A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90.

1 reference

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7 January 2021

Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

1 reference

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7 January 2021

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

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https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase

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7 January 2021

Reduced levels of hsp90 compromise steroid receptor action in vivo

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7 January 2021

Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase

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7 January 2021

Cdc37: a protein kinase chaperone?

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7 January 2021

A Novel Glycosaminoglycan-binding Protein Is the Vertebrate Homologue of the Cell Cycle Control Protein, Cdc37

1 reference

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7 January 2021

A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

CDC37 is required for p60v-src activity in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Reconstitution of progesterone receptor with heat shock proteins

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7 January 2021

A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The assembly of progesterone receptor-hsp90 complexes using purified proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Studies with Purified Chaperones Advance the Understanding of the Mechanism of Glucocorticoid Receptor-hsp90 Heterocomplex Assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Animal and plant cell lysates share a conserved chaperone system that assembles the glucocorticoid receptor into a functional heterocomplex with hsp90.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

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7 January 2021

Recent Advances in the Study of hsp90 Structure and Mechanism of Action

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7 January 2021

Nucleotides and two functional states of hsp90

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https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Molecular chaperones in cellular protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Isolation and characterization of STI1, a stress-inducible gene from Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Hop modulates Hsp70/Hsp90 interactions in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Hop as an adaptor in the heat shock protein 70 (Hsp70) and hsp90 chaperone machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes

1 reference

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7 January 2021

The importance of ATP binding and hydrolysis by hsp90 in formation and function of protein heterocomplexes

1 reference

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7 January 2021

Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins

1 reference

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7 January 2021

BAG-1 modulates the chaperone activity of Hsp70/Hsc70

1 reference

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7 January 2021

Characterization of interactions between the anti-apoptotic protein BAG-1 and Hsc70 molecular chaperones

1 reference

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7 January 2021

Control of steroid receptor function and cytoplasmic-nuclear transport by heat shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

A conserved proline in the hsp90 binding region of the glucocorticoid receptor is required for hsp90 heterocomplex stabilization and receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

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7 January 2021

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

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7 January 2021

Nucleocytoplasmic trafficking of steroid-free glucocorticoid receptor

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7 January 2021

Chromatin recycling of glucocorticoid receptors: implications for multiple roles of heat shock protein 90

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7 January 2021

Inhibition of glucocorticoid receptor nucleocytoplasmic shuttling by okadaic acid requires intact cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The hsp56 immunophilin component of steroid receptor heterocomplexes: could this be the elusive nuclear localization signal-binding protein?

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

A 59-kilodalton protein associated with progestin, estrogen, androgen, and glucocorticoid receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The 56-59-kilodalton protein identified in untransformed steroid receptor complexes is a unique protein that exists in cytosol in a complex with both the 70- and 90-kilodalton heat shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

An active FK506-binding domain of 17,000 daltons is isolated following limited proteolysis of chicken thymus hsp56

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Overexpression of p59-HBI (FKBP59), full length and domains, and characterization of PPlase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The mammalian heat shock protein binding immunophilin (p59/HBI) is an ATP and GTP binding protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Rabbit FKBP59-heat shock protein binding immunophillin (HBI) is a calmodulin binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Phosphorylation of the immunosuppressant FK506-binding protein FKBP52 by casein kinase II: Regulation of HSP90-binding activity of FKBP52

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Isolation of untransformed bovine estrogen receptor without molybdate stabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The Cyclosporin A-binding Immunophilin CyP-40 and the FK506-binding Immunophilin hsp56 Bind to a Common Site on hsp90 and Exist in Independent Cytosolic Heterocomplexes with the Untransformed Glucocorticoid Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: a possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

FK506 binding to the 56-kilodalton immunophilin (hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Functional analysis of the yeast 40 kDa cyclophilin Cyp40 and its role for viability and steroid receptor regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Differential interactions of p23 and the TPR-containing proteins Hop, Cyp40, FKBP52 and FKBP51 with Hsp90 mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The common tetratricopeptide repeat acceptor site for steroid receptor-associated immunophilins and hop is located in the dimerization domain of Hsp90.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Identification of conserved residues required for the binding of a tetratricopeptide repeat domain to heat shock protein 90.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Binding of immunophilins to the 90 kDa heat shock protein (hsp90) via a tetratricopeptide repeat domain is a conserved protein interaction in plants

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

High-molecular-weight FK506-binding proteins are components of heat-shock protein 90 heterocomplexes in wheat germ lysate

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Analysis of FKBP51/FKBP52 chimeras and mutants for Hsp90 binding and association with progesterone receptor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Characterization of the Ah receptor-associated protein, ARA9

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

The role of the aryl hydrocarbon receptor nuclear translocator protein in aryl hydrocarbon receptor action

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Demonstration by confocal microscopy that unliganded overexpressed glucocorticoid receptors are distributed in a nonrandom manner throughout all planes of the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Transit of pp60v-src to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2899%2900064-9

7 January 2021

10.1016/S0898-6568(99)00064-9

Identifiers

DOI

1 reference

29 July 2017

1 reference