(Q33800739)

29 July 2017

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title

Expression of hypoxia-inducible factor 1: mechanisms and consequences (English)

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29 July 2017

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Semenza GL

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29 July 2017

language of work or name

English

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publication date

1 January 2000

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29 July 2017

published in

Biochemical Pharmacology

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

47-53

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

29 July 2017

cites work

1 reference

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General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

7 January 2021

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Hypoxia-inducible factor 1: master regulator of O2 homeostasis

7 January 2021

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Purification and characterization of hypoxia-inducible factor 1

7 January 2021

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

7 January 2021

1 reference

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

7 January 2021

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

7 January 2021

1 reference

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Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor

7 January 2021

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Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

7 January 2021

1 reference

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Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

7 January 2021

1 reference

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 January 2021

1 reference

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Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

7 January 2021

1 reference

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 January 2021

1 reference

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Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

7 January 2021

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Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

7 January 2021

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Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

7 January 2021

1 reference

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Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer

7 January 2021

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Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

7 January 2021

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Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1

7 January 2021

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Role of hydrogen peroxide in hypoxia-induced erythropoietin production

7 January 2021

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Photometric characteristics of haem proteins in erythropoietin-producing hepatoma cells (HepG2).

7 January 2021

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Cytochromes and oxygen radicals as putative members of the oxygen sensing pathway

7 January 2021

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Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing

7 January 2021

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

7 January 2021

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Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes.

7 January 2021

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

7 January 2021

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α

7 January 2021

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

7 January 2021

1 reference

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

7 January 2021

1 reference

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Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death

7 January 2021

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Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

7 January 2021

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

7 January 2021

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Angiogenesis and tumor metastasis

7 January 2021

1 reference

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

7 January 2021

1 reference

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Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

7 January 2021

1 reference

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Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

7 January 2021

1 reference

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

7 January 2021

1 reference

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Gene expression profiles in normal and cancer cells

7 January 2021

1 reference

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Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species.

7 January 2021

2 references

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900292-0

inferred from DOI database lookup

7 January 2021

based on heuristic

Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900292-0

10.1016/S0006-2952(99)00292-0

7 January 2021

Identifiers

DOI

1 reference

29 July 2017

1 reference