(Q33894534)

29 July 2017

title

On the opposing views of the self-nonself discrimination by the immune system (English)

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29 July 2017

Melvin Cohn

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29 July 2017

publication date

2 December 2008

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Immunology & Cell Biology

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

113-9, discussion 120-1

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A rationalized set of default postulates that permit a coherent description of the immune system amenable to computer modeling

29 July 2017

cites work

1 reference

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What roles do regulatory T cells play in the control of the adaptive immune response?

5 July 2018

1 reference

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The Tritope Model for restrictive recognition of antigen by T-cells II. Implications for ontogeny, evolution and physiology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Time, space and contextual models of the immunity tolerance decision: bridging the geographical divide of Zinkernagel and Hengartner's 'Credo 2004'.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

THE NATURAL-SELECTION THEORY OF ANTIBODY FORMATION

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

The Tritope Model for restrictive recognition of antigen by T-cells I. What assumptions about structure are needed to explain function?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A biological context for the self-nonself discrimination and the regulation of effector class by the immune system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

The common sense of the self-nonself discrimination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Self-nonself discrimination by T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

On immunity against infections and vaccines: credo 2004.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

If the "adaptive" immune system can recognize a significant portion of the pathogenic universe to which the "innate" immune system is blind, then...

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Whither T-suppressors: if they didn't exist would we have to invent them?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

An alternative to current thinking about positive selection, negative selection and activation of T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Actively acquired tolerance of foreign cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A computerized model for the self-non-self discrimination at the level of the Th (Th genesis). II. The behavior of the system upon encounter with non-self antigens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Tritope model of restrictive recognition by the TCR.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

If the immune repertoire evolved to be large, random, and somatically generated, then...

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A computerized model for the self-non-self discrimination at the level of the T(h) (Th genesis). I. The origin of 'primer' effector T(h) cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A minimal model for the self-nonself discrimination: a return to the basics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

The standard model of T-cell receptor function: a critical reassessment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

The self-nonself discrimination in the context of function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A two-step, two-signal model for the primary activation of precursor helper T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Mechanisms of tolerance to self

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A short history of time and space in immune discrimination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Tolerance, danger, and the extended family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

The self/nonself discrimination: reconstructing a cabbage from sauerkraut

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

Was everyone a “little bit right” after all?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A new analysis of allogeneic interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880885

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2008.96

21 January 2018

Allergy and Immunology

1 reference

https://api.crossref.org/works/10.1038%2FICB.2008.96

Testing time-, ignorance-, and danger-based models of tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2008.96

Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2008.96

The Th1/Th2 nature of concurrent immune responses to unrelated antigens can be independent

21 January 2018

1 reference

12 December 2020

The self-nonself discrimination is not regulated by suppression

1 reference

12 December 2020

Two signal models of lymphocyte activation?

1 reference

12 December 2020

On 'Credo 2004' as viewed under the 'development-context' model of Colin Anderson

1 reference

12 December 2020

Identifiers

DOI

10.1038/ICB.2008.96

1 reference

29 July 2017

1 reference

29 July 2017

1 reference