(Q33877024)

29 July 2017

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title

Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies (English)

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29 July 2017

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Brown JM

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29 July 2017

publication date

1 April 2000

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Trends in Molecular Medicine

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

157-162

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The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy

29 July 2017

cites work

1 reference

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7 January 2021

Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

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7 January 2021

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

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7 January 2021

Oxygenation predicts radiation response and survival in patients with cervix cancer

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7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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7 January 2021

The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target

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7 January 2021

Potential bioreductive alkylating agents. 1. Benzoquinone derivatives

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7 January 2021

Mitomycin-C as a prototype bioreductive alkylating agent: in vitro studies of metabolism and cytotoxicity

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7 January 2021

Hypoxia-Specific Cytotoxins in Cancer Therapy

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7 January 2021

Mitomycin C as an adjunct to postoperative radiation therapy in squamous cell carcinoma of the head and neck: Results from two randomized clinical trials

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7 January 2021

SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells

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7 January 2021

Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin

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7 January 2021

Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent

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7 January 2021

AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo

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7 January 2021

Enhancement of the anti-tumour effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine

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7 January 2021

Hypoxia-inducible factor 1: master regulator of O2 homeostasis

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901677-4

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901677-4

7 January 2021

Development of a hypoxia-responsive vector for tumor-specific gene therapy

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901677-4

7 January 2021

SR 4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours

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https://api.crossref.org/works/10.1016%2FS1357-4310%2800%2901677-4

7 January 2021

10.1016/S1357-4310(00)01677-4

Identifiers

DOI

1 reference

29 July 2017

1 reference