(Q33873705)

29 July 2017

title

Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression (English)

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29 July 2017

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Marie-Solange Mutabaruka

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29 July 2017

Mohamed Aoulad Aissa

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29 July 2017

Aline Delalandre

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29 July 2017

Martin Lavigne

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29 July 2017

Daniel Lajeunesse

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29 July 2017

publication date

8 February 2010

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Arthritis Research and Therapy

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

R20

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Leptin increases osteoblast-specific osteocalcin release through a hypothalamic relay

29 July 2017

cites work

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Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Leptin increases proliferation of human steosarcoma cells through activation of PI(3)-K and MAPK pathways

5 July 2018

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Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Human adult chondrocytes express hepatocyte growth factor (HGF) isoforms but not HgF: potential implication of osteoblasts on the presence of HGF in cartilage

5 July 2018

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5 July 2018

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5 July 2018

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Leptin receptor isoform expression in rat osteoblasts and their functional analysis.

5 July 2018

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Role of leptin in bone growth: central player or peripheral supporter?

5 July 2018

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5 July 2018

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Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients

5 July 2018

1 reference

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Leptin promotes the tyrosine phosphorylation of SHC proteins and SHC association with GRB2.

5 July 2018

1 reference

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Human articular chondrocytes express functional leptin receptors

5 July 2018

1 reference

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Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Retinoic acid and vitamin D(3) powerfully inhibit in vitro leptin secretion by human adipose tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Endogenous prostaglandin E2 and insulin-like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Leptin is a potent stimulator of bone growth in ob/ob mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Activation of downstream signals by the long form of the leptin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Importance of subchondral bone to articular cartilage in health and disease

5 July 2018

1 reference

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Direct effects of leptin on brown and white adipose tissue

5 July 2018

1 reference

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Direct antidiabetic effect of leptin through triglyceride depletion of tissues.

5 July 2018

1 reference

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Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Modulation of insulin activities by leptin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Identification and expression cloning of a leptin receptor, OB-R

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Positional cloning of the mouse obese gene and its human homologue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Bone density, osteoarthrosis of the hip, and fracture of the upper end of the femur

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Bone mass in osteoarthrosis, measured in vivo by photon absorption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Measurement of protein using bicinchoninic acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

The biology of osteoarthritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Leptin increases growth of primary ossification centers in fetal mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

CXCL12 (SDF-1) and CXCL13 (BCA-1) chemokines significantly induce proliferation and collagen type I expression in osteoblasts from osteoarthritis patients

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Immunocytochemical detection of phosphatidylinositol 3-kinase activation by insulin and leptin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Leptin: a review of its peripheral actions and interactions

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Regulation of Jak kinases by intracellular leptin receptor sequences.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Leptin acts as a growth factor on the chondrocytes of skeletal growth centers

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: possible role in subchondral bone sclerosis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875652

Correlation of synovial fluid leptin concentrations with the severity of osteoarthritis

29 October 2018

1 reference

12 December 2020

Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans

1 reference

12 December 2020

The effect of leptin on Lep expression is tissue-specific and nutritionally regulated

1 reference

12 December 2020

Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways

1 reference

12 December 2020

Collagen and non-collagenous protein content (osteocalcin, sialoprotein, proteoglycan) in the iliac crest bone and serum osteocalcin in women with and without hand osteoarthritis

1 reference

12 December 2020

Obesity and Knee Osteoarthritis

1 reference

12 December 2020

Epidemiology of osteoarthritis

1 reference

12 December 2020

Growth and development in simple obesity

1 reference

12 December 2020

Microcracks in the calcified layer of articular cartilage

1 reference

12 December 2020

Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosi

1 reference

12 December 2020

Correlation between synovial fluid markers of cartilage and bone turnover and scintigraphic scan abnormalities in osteoarthritis of the knee.

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR2925

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

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