(Q33717057)

28 July 2017

title

Modularity of the Hrd1 ERAD complex underlies its diverse client range (English)

1 reference

28 July 2017

Kazue Kanehara

1 reference

28 July 2017

Wei Xie

series ordinal

1 reference

28 July 2017

Davis T W Ng

series ordinal

1 reference

28 July 2017

language of work or name

English

0 references

publication date

1 March 2010

1 reference

28 July 2017

published in

Journal of Cell Biology

1 reference

28 July 2017

volume

188

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28 July 2017

1 reference

28 July 2017

page(s)

707-716

1 reference

describes a project that uses

28 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2835937/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

21 June 2018

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21 June 2018

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Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp

21 June 2018

1 reference

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Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.

21 June 2018

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Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

21 June 2018

1 reference

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21 June 2018

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The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

21 June 2018

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21 June 2018

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Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ.

21 June 2018

1 reference

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21 June 2018

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Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation

21 June 2018

1 reference

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Yos9 protein is essential for degradation of misfolded glycoproteins and may function as lectin in ERAD.

21 June 2018

1 reference

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Yos9p detects and targets misfolded glycoproteins for ER-associated degradation

21 June 2018

1 reference

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Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen

21 June 2018

1 reference

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Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation

21 June 2018

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A genome-wide screen identifies Yos9p as essential for ER-associated degradation of glycoproteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

A membrane protein required for dislocation of misfolded proteins from the ER

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Quality control in the endoplasmic reticulum protein factory

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

ER protein quality control and proteasome-mediated protein degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Ste6p mutants defective in exit from the endoplasmic reticulum (ER) reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Elimination of Defective α-Factor Pheromone Receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

A pathway for targeting soluble misfolded proteins to the yeast vacuole

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

N-Glycosylation affects endoplasmic reticulum degradation of a mutated derivative of carboxypeptidase yscY in yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Expression of wild-type and mutant forms of influenza hemagglutinin: the role of folding in intracellular transport

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

Quality control in the endoplasmic reticulum: folding and misfolding of vesicular stomatitis virus G protein in cells and in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835937

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200907055

Multiple endoplasmic reticulum-associated pathways degrade mutant yeast carboxypeptidase Y in mammalian cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200907055

Cell biology. Protein degradation unlocked

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200907055

Importance of carbohydrate positioning in the recognition of mutated CPY for ER-associated degradation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20212318

12 December 2020

inferred from PubMed ID database lookup

Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20212318

12 December 2020

inferred from PubMed ID database lookup

Ricin A chain utilises the endoplasmic reticulum-associated protein degradation pathway to enter the cytosol of yeast

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20212318

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.200907055

1 reference

28 July 2017

1 reference

28 July 2017

1 reference