(Q33759296)

29 July 2017

title

Activation of the A(3) adenosine receptor inhibits fMLP-induced Rac activation in mouse bone marrow neutrophils (English)

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29 July 2017

author name string

Dharini van der Hoeven

series ordinal

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29 July 2017

Elizabeth T Gizewski

series ordinal

1 reference

29 July 2017

John A Auchampach

series ordinal

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29 July 2017

language of work or name

English

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publication date

10 February 2010

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29 July 2017

published in

Biochemical Pharmacology

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

1667-1673

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Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

29 July 2017

cites work

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Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils

21 June 2018

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The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel

21 June 2018

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Cl-IB-MECA [2-chloro-N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide] reduces ischemia/reperfusion injury in mice by activating the A3 adenosine receptor

21 June 2018

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21 June 2018

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21 June 2018

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Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity

21 June 2018

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P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Calcium signaling regulates translocation and activation of Rac.

21 June 2018

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Signalling from adenosine receptors to mitogen-activated protein kinases

21 June 2018

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Ca2+-independent protein kinase Cs mediate heterologous desensitization of leukocyte chemokine receptors by opioid receptors

21 June 2018

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21 June 2018

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P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

21 June 2018

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21 June 2018

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Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways

21 June 2018

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Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency

21 June 2018

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Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

21 June 2018

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Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells

21 June 2018

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Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

21 June 2018

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Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

21 June 2018

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21 June 2018

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21 June 2018

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Chemoattractant signaling and leukocyte activation

21 June 2018

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A new generation of Ca2+ indicators with greatly improved fluorescence properties

21 June 2018

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Receptor class desensitization of leukocyte chemoattractant receptors

21 June 2018

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ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.

21 June 2018

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Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass

30 October 2018

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Evidence for functional adenosine A3 receptors in microglia cells

30 October 2018

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Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847012

Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847012

Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847012

Accelerated resequestration of cytosolic calcium and suppression of the pro-inflammatory activities of human neutrophils by CGS 21680 in vitro

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847012

Gelsolin is a downstream effector of rac for fibroblast motility

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847012

Adenosine A3 receptor expression and function in eosinophils

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847012

Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847012

A(3) adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury

30 October 2018

1 reference

12 December 2020

Reversal of the antiinflammatory effects of methotrexate by the nonselective adenosine receptor antagonists theophylline and caffeine: evidence that the antiinflammatory effects of methotrexate are mediated via multiple adenosine receptors in rat ad

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12 December 2020

Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2

1 reference

12 December 2020

The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils

1 reference

12 December 2020

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

1 reference

12 December 2020

Adenosine A3 receptor stimulation inhibits migration of human eosinophils

1 reference

12 December 2020

The Small GTP-binding Protein Rac Promotes the Dissociation of Gelsolin from Actin Filaments in Neutrophils

1 reference

12 December 2020

p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation

1 reference

12 December 2020

Regulation of p21rac activation in human neutrophils

1 reference

12 December 2020

Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways

1 reference

12 December 2020

A3 adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis

1 reference

12 December 2020

10.1016/J.BCP.2010.02.002

Identifiers

DOI

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29 July 2017

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29 July 2017

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