(Q33680168)

28 July 2017

title

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine (English)

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28 July 2017

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28 July 2017

Dominique Guianvarc'h

object named as

Dominique Guianvarc'h

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Paola B Arimondo

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Catherine Sénamaud-Beaufort

28 July 2017

series ordinal

object named as

Catherine Sénamaud-Beaufort

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28 July 2017

Renata Z Jurkowska

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28 July 2017

Christine Champion

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28 July 2017

Loïc Ponger

series ordinal

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28 July 2017

Anne-Laure Guieysse-Peugeot

series ordinal

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28 July 2017

language of work or name

English

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publication date

24 August 2010

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

e12388

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Creative Commons Attribution 4.0 International

28 July 2017

start time

24 August 2010

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Zebularine: a new drug for epigenetic therapy

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Kinetics and Mechanisms of Degradation of the Antileukemic Agent 5‐Azacytidine in Aqueous Solutions

21 June 2018

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21 June 2018

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The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor

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Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (zebularine) at the GCGC recognition domain

21 January 2018

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Inhibition of DNA methylation and reactivation of silenced genes by zebularine

21 January 2018

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Angiostatic activity of DNA methyltransferase inhibitors

21 January 2018

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Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice.

21 January 2018

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Mutagenicity of the cytidine analog zebularine in Escherichia coli

21 January 2018

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A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT).

21 January 2018

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Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme

21 January 2018

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Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

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12 December 2020

High-performance Liquid Chromatographic Analysis of Chemical Stability of 5-aza-2′-Deoxycytidine

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12 December 2020

Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine

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Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA

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12 December 2020

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12 December 2020

10.1371/JOURNAL.PONE.0012388

Identifiers

DOI

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28 July 2017

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28 July 2017

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