(Q33589965)

28 July 2017

title

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease (English)

1 reference

28 July 2017

0 references

Jeong-Sun Ju

1 reference

28 July 2017

Rodrigo A Fuentealba

0 references

Robert H Baloh

1 reference

28 July 2017

David Piwnica-Worms

1 reference

28 July 2017

Conrad C Weihl

1 reference

28 July 2017

Sara E Miller

1 reference

28 July 2017

Erin Jackson

series ordinal

1 reference

28 July 2017

language of work or name

English

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publication date

1 December 2009

1 reference

28 July 2017

published in

Journal of Cell Biology

1 reference

28 July 2017

volume

187

1 reference

28 July 2017

1 reference

28 July 2017

page(s)

875-888

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2806317/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

14 July 2018

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Valosin-containing protein disease: inclusion body myopathy with Paget's disease of the bone and fronto-temporal dementia

14 July 2018

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RETRACTED: VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification

14 July 2018

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14 July 2018

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Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

14 July 2018

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VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death

14 July 2018

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Amyloid-beta accumulation caused by chloroquine injections precedes ER stress and autophagosome formation in rat skeletal muscle

14 July 2018

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14 July 2018

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TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia

14 July 2018

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Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease

14 July 2018

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Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease

14 July 2018

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14 July 2018

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14 July 2018

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

14 July 2018

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FoxO3 controls autophagy in skeletal muscle in vivo

14 July 2018

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Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

14 July 2018

1 reference

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

14 July 2018

1 reference

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Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

14 July 2018

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The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy

14 July 2018

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

14 July 2018

1 reference

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Pathological consequences of VCP mutations on human striated muscle

14 July 2018

1 reference

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p97: The cell's molecular purgatory?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Electron microscopy in neuromuscular disorders

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degeneration

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

In search of an "autophagomometer".

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

An Italian family with inclusion-body myopathy and frontotemporal dementia due to mutation in the VCP gene.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Valosin-containing protein gene mutations: clinical and neuropathologic features

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Mutant valosin-containing protein causes a novel type of frontotemporal dementia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

Exocytotic “constipation” is a mechanism of tubulin/lysosomal interaction in colchicine myopathy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806317

TDP-43 accumulation is common in myopathies with rimmed vacuoles

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20008565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20008565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200908115

1 reference

28 July 2017

1 reference

28 July 2017

1 reference