(Q33550002)

28 July 2017

title

Early aggregation steps in alpha-synuclein as measured by FCS and FRET: evidence for a contagious conformational change. (English)

1 reference

28 July 2017

1 reference

Jelle Hendrix

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28 July 2017

Yves Engelborghs

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28 July 2017

Sangeeta Nath

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28 July 2017

Jessika Meuvis

series ordinal

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28 July 2017

Shaun A Carl

series ordinal

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28 July 2017

language of work or name

English

0 references

publication date

1 April 2010

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

1302-1311

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Structural characterization of alpha-synuclein in an aggregation prone state.

28 July 2017

cites work

1 reference

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Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence.

21 June 2018

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Alpha-synuclein aggregation variable temperature and variable pH kinetic data: a re-analysis using the Finke-Watzky 2-step model of nucleation and autocatalytic growth

21 June 2018

1 reference

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Protein aggregation kinetics, mechanism, and curve-fitting: a review of the literature.

21 June 2018

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The fold of alpha-synuclein fibrils

21 June 2018

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Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic surface growth

21 June 2018

1 reference

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The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates

21 June 2018

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Redesigning protein pKa values.

21 June 2018

1 reference

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Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from alpha-synuclein mutants

21 June 2018

1 reference

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The aggregation and fibrillation of alpha-synuclein

21 June 2018

1 reference

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Helix periodicity, topology, and dynamics of membrane-associated alpha-synuclein

21 June 2018

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Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters

21 June 2018

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Distribution, lateral mobility and function of membrane proteins incorporated into giant unilamellar vesicles

21 June 2018

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Alpha-synuclein structures from fluorescence energy-transfer kinetics: implications for the role of the protein in Parkinson's disease

21 June 2018

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Correct diffusion coefficients of proteins in fluorescence correlation spectroscopy. Application to tubulin oligomers induced by Mg2+ and Paclitaxel

21 June 2018

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Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

21 June 2018

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DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy

21 June 2018

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Alpha-synuclein and neurodegenerative diseases

21 June 2018

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Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 June 2018

1 reference

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Amyloid beta-peptide polymerization studied using fluorescence correlation spectroscopy

21 June 2018

1 reference

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Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synuclein

21 June 2018

1 reference

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Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

31 October 2018

1 reference

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Multiparametric fluorescence detection of early stages in the amyloid protein aggregation of pyrene-labeled alpha-synuclein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849099

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers

31 October 2018

1 reference

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A fast and sensitive method for measuring the integrity of siRNA-carrier complexes in full human serum

31 October 2018

1 reference

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Different species of alpha-synuclein oligomers induce calcium influx and seeding.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849099

Real-time enzyme dynamics illustrated with fluorescence spectroscopy of p-hydroxybenzoate hydroxylase.

31 October 2018

1 reference

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Temperature-induced reversible conformational change in the first 100 residues of alpha-synuclein

31 October 2018

1 reference

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The aggregation of alpha-synuclein is stimulated by FK506 binding proteins as shown by fluorescence correlation spectroscopy

31 October 2018

1 reference

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Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.

31 October 2018

1 reference

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Evidence for a partially folded intermediate in alpha-synuclein fibril formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849099

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

31 October 2018

1 reference

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Tetramethylrhodamine dimer formation as a spectroscopic probe of the conformation of Escherichia coli ribosomal protein L7/L12 dimers

10 December 2018

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12 December 2020

Single particle detection and characterization of synuclein co-aggregation

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12 December 2020

Time-resolved fluorescence of tryptophans in yeast hexokinase-PI: effect of subunit dimerization and ligand binding

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12 December 2020

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease

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12 December 2020

Secondary structural formation of alpha-synuclein amyloids as revealed by g-factor of solid-state circular dichroism

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12 December 2020

High yield selective acylation of polyamines: proton as protecting group

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12 December 2020

Membrane-bound structure and energetics of alpha-synuclein

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12 December 2020

10.1016/J.BPJ.2009.12.4290

Identifiers

DOI

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28 July 2017

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28 July 2017

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