(Q33309163)

25 July 2017

title

Integrating high-content screening and ligand-target prediction to identify mechanism of action (English)

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25 July 2017

Jeremy L Jenkins

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Andreas Bender

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25 July 2017

Daniel W Young

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25 July 2017

Jonathan Hoyt

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25 July 2017

Elizabeth McWhinnie

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25 July 2017

Gung-Wei Chirn

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25 July 2017

Charles Y Tao

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25 July 2017

John A Tallarico

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25 July 2017

Mark Labow

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25 July 2017

Timothy J Mitchison

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25 July 2017

Yan Feng

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25 July 2017

publication date

9 December 2007

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25 July 2017

published in

Nature Chemical Biology

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25 July 2017

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25 July 2017

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25 July 2017

page(s)

59-68

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The principle of complementarity: chemical versus biological space

25 July 2017

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New methods for ligand-based virtual screening: use of data fusion and machine learning to enhance the effectiveness of similarity searching

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Aurantimycins, new depsipeptide antibiotics from Streptomyces aurantiacus IMET 43917. Production, isolation, structure elucidation, and biological activity.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Cytometric analysis of DNA replication inhibited by emetine and cyclosporin A.

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7 January 2021

Expression of progesterone receptor B is associated with G0/G1 arrest of the cell cycle and growth inhibition in NIH3T3 cells

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7 January 2021

Microtubule-interacting drugs for cancer treatment

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7 January 2021

Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin.

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7 January 2021

Complex phenotypic assays in high-throughput screening

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7 January 2021

Image-based multivariate profiling of drug responses from single cells

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7 January 2021

A discussion of measures of enrichment in virtual screening: comparing the information content of descriptors with increasing levels of sophistication

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7 January 2021

Bridging chemical and biological space: "target fishing" using 2D and 3D molecular descriptors

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7 January 2021

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7 December 2024

Identifiers

DOI

10.1038/NCHEMBIO.2007.53

1 reference

25 July 2017

1 reference