(Q33223661)

24 July 2017

title

Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobacterium tuberculosis (English)

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Mycobacterium tuberculosis

24 July 2017

main subject

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Stephen Douthwaite

1 reference

24 July 2017

Jean-Luc Pernodet

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Christian Toft Madsen

1 reference

24 July 2017

Lene Jakobsen

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24 July 2017

Karolina Buriánková

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24 July 2017

Florence Doucet-Populaire

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24 July 2017

language of work or name

English

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publication date

20 September 2005

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Journal of Biological Chemistry

24 July 2017

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inferred from page(s)

published in

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24 July 2017

volume

280

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24 July 2017

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24 July 2017

page(s)

38942-38947

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Erasing the World's Slow Stain: Strategies to Beat Multidrug-Resistant Tuberculosis

24 July 2017

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In vitro activities of the ketolides telithromycin (HMR 3647) and HMR 3004 compared to those of clarithromycin against slowly growing mycobacteria at pHs 6.8 and 7.4

21 January 2018

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Clarithromycin is inactive against Mycobacterium tuberculosis

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Intrinsic resistance of Mycobacterium tuberculosis to clarithromycin is effectively reversed by subinhibitory concentrations of cell wall inhibitors.

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Molecular basis of intrinsic macrolide resistance in the Mycobacterium tuberculosis complex

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Methylation of 23S ribosomal RNA due to carB, an antibiotic-resistance determinant from the carbomycin producer, Streptomyces thermotolerans

21 January 2018

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Activity of the ketolide telithromycin is refractory to Erm monomethylation of bacterial rRNA.

21 January 2018

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Comparative genomics of BCG vaccines by whole-genome DNA microarray

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Effect of pH on radiometric MICs of clarithromycin against 18 species of mycobacteria

21 January 2018

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A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNA

21 January 2018

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Detection of pseudouridine and other modifications in tRNA by cyanoethylation and MALDI mass spectrometry

21 January 2018

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Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry

21 January 2018

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Intrinsic Macrolide Resistance in Mycobacterium smegmatis Is Conferred by a Novel erm Gene, erm (38)

21 January 2018

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23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G.

21 January 2018

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Mycobacterium smegmatis Erm(38) is a reluctant dimethyltransferase

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance

21 January 2018

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Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria

21 January 2018

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The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism

21 January 2018

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Identification of essential residues in the Erm(B) rRNA methyltransferase of Clostridium perfringens

21 January 2018

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Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'.

21 January 2018

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Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions

21 January 2018

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Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants

21 January 2018

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Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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RNA fragmentation studied in a matrix-assisted laser desorption/ionisation tandem quadrupole/orthogonal time-of-flight mass spectrometer

21 January 2018

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Genomic sequence and transcriptional analysis of a 23-kilobase mycobacterial linear plasmid: evidence for horizontal transfer and identification of plasmid maintenance systems

21 January 2018

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Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

21 January 2018

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21 January 2018

New fronts in an old war

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21 January 2018

Identifiers

DOI

10.1074/JBC.M505727200

1 reference

24 July 2017

1 reference