(Q32134580)

6 July 2017

title

Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis (English)

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6 July 2017

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Gary DS

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6 July 2017

Mattson MP

series ordinal

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6 July 2017

language of work or name

English

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publication date

1 March 2001

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Journal of Neurochemistry

6 July 2017

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inferred from page(s)

published in

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6 July 2017

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6 July 2017

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6 July 2017

page(s)

1485-1496

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Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

6 July 2017

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1 reference

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p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

21 January 2018

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Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

21 January 2018

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Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

21 January 2018

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Pro-apoptotic action of PAR-4 involves inhibition of NF-kappaB activity and suppression of BCL-2 expression

21 January 2018

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Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

21 January 2018

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Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin

21 January 2018

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NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

21 January 2018

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Micromolar L-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurones.

21 January 2018

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Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

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Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

21 January 2018

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Pathobiology of ischaemic stroke: an integrated view

21 January 2018

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The role of excitotoxicity in neurodegenerative disease: implications for therapy

21 January 2018

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Enhanced in vitro survival and growth of foetal human mesencephalic dopaminergic neurones on laminin and collagen: implications for cell banking.

21 January 2018

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Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons

21 January 2018

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Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling

21 January 2018

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21 January 2018

Integrins and anoikis

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21 January 2018

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Anatomical Localization of β1 Integrin-like Immunoreactivity in Rat Brain

21 January 2018

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Integrin-mediated short-term memory in Drosophila

21 January 2018

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Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

21 January 2018

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Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

21 January 2018

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Laminin-like antigen in rat CNS neurons: distribution and changes upon brain injury and nerve growth factor treatment.

21 January 2018

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Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

21 January 2018

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Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

21 January 2018

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Laminins in the adult and aged brain

21 January 2018

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

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Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation

21 January 2018

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

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The proto-oncogene Bcl-2 and its role in regulating apoptosis

21 January 2018

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Extracellular matrix degradation by metalloproteinases and central nervous system diseases

21 January 2018

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PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

21 January 2018

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Neuroprotective signal transduction: relevance to stroke

21 January 2018

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Apoptosis in neurodegenerative disorders

21 January 2018

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Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons

21 January 2018

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Activation of NF-?B protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration

21 January 2018

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Evidence for synaptic apoptosis

21 January 2018

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Apoptotic and antiapoptotic mechanisms in stroke.

21 January 2018

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Roles of nuclear factor kappaB in neuronal survival and plasticity

21 January 2018

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HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells

21 January 2018

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Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury?

21 January 2018

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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Recent advances on the pathogenesis of Huntington's disease

21 January 2018

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Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

21 January 2018

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Transforming growth factor-beta 1 prevents glutamate neurotoxicity in rat neocortical cultures and protects mouse neocortex from ischemic injury in vivo

21 January 2018

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Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

BDNF and NT-3 but not CNTF counteract the Ca2+ ionophore-induced apoptosis of cultured cortical neurons: involvement of dual pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

Integrins at the neuromuscular junction are important for motoneuron survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

Fibronectin interaction with α4β1 integrin prevents apoptosis in B cell chronic lymphocytic leukemia: correlation with Bcl-2 and Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

Akt is more than just a Bad kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2001.00173.X

10.1046/J.1471-4159.2001.00173.X

21 January 2018

Identifiers

DOI

1 reference

6 July 2017

1 reference