(Q31063920)

28 June 2017

title

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets (English)

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genome-wide association study

28 June 2017

main subject

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28 June 2017

Han Hu

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Andrew Bakshi

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Futao Zhang

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Matthew R Robinson

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Jian Yang

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Naomi R Wray

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Grant W Montgomery

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Zhihong Zhu

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Michael E Goddard

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Joseph E Powell

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28 June 2017

language of work or name

English

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publication date

28 March 2016

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28 June 2017

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28 June 2017

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28 June 2017

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28 June 2017

page(s)

481-487

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describes a project that uses

28 June 2017

genome-wide association study

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based on heuristic

inferred from title

cites work

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

1 reference

Obesity-associated variants within FTO form long-range functional connections with IRX3

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FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

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KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant

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Association between microdeletion and microduplication at 16p11.2 and autism

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Microduplications of 16p11.2 are associated with schizophrenia

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Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

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Biological insights from 108 schizophrenia-associated genetic loci

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Systematic identification of trans eQTLs as putative drivers of known disease associations

21 January 2018

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Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects

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TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

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Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

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Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

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Overlap of expression quantitative trait loci (eQTL) in human brain and blood

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Partitioning heritability by functional annotation using genome-wide association summary statistics

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1 reference

Association of schizophrenia and autoimmune diseases: linkage of Danish national registers

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Schizophrenia and the gut–brain axis

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Genetic variability in the regulation of gene expression in ten regions of the human brain

21 January 2018

1 reference

Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data

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1 reference

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

21 January 2018

1 reference

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

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1 reference

Bayesian test for colocalisation between pairs of genetic association studies using summary statistics

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1 reference

A gene-based association method for mapping traits using reference transcriptome data

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1 reference

Integrative approaches for large-scale transcriptome-wide association studies

21 January 2018

1 reference

The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics

21 January 2018

1 reference

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

21 January 2018

1 reference

Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis

21 January 2018

1 reference

Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators

21 January 2018

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Two-Sample Instrumental Variables Estimators

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The International HapMap Project

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Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts

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A map of human genome variation from population-scale sequencing

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GCTA: a tool for genome-wide complex trait analysis

21 January 2018

1 reference

The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis

21 January 2018

1 reference

TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27019110

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27019110

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.3538

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Dimensions Publication ID

28 June 2017

1013588188

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