(Q30494019)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Kenneth W Wood

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Latesh Lad

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Lusong Luo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Xiangping Qian

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Steven D Knight

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

David Sutton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Aidan G Gilmartin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Penelope R Chua

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Radhika Desai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Stephen P Schauer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Dean E McNulty

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Roland S Annan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Lisa D Belmont

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Carlos Garcia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Yan Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Melody A Diamond

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Leo F Faucette

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Michele Giardiniere

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Shuyun Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Chiu-Mei Sun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Justin D Vidal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Serge Lichtsteiner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

William D Cornwell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Joel D Greshock

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Richard F Wooster

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Jeffrey T Finer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Robert A Copeland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Pearl S Huang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

David J Morgans

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Dashyant Dhanak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Gustave Bergnes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Roman Sakowicz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Jeffrey R Jackson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

18 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

5839-5844

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.

18 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Distinct concentration-dependent effects of the polo-like kinase 1-specific inhibitor GSK461364A, including differential effect on apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Centromere-associated protein E: a motor that puts the brakes on the mitotic checkpoint

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Chromosomes can congress to the metaphase plate before biorientation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Crystal structure of the motor domain of the human kinetochore protein CENP-E

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Antitumor activity of a kinesin inhibitor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

A structural pathway for activation of the kinesin motor ATPase.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

The way things move: looking under the hood of molecular motor proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

15 A resolution model of the monomeric kinesin motor, KIF1A.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

A processive single-headed motor: kinesin superfamily protein KIF1A.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

CENP-E function at kinetochores is essential for chromosome alignment.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Development and validation of a genetic algorithm for flexible docking

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Pathway of processive ATP hydrolysis by kinesin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

CENP-E is a putative kinetochore motor that accumulates just before mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851928

Aneuploidy acts both oncogenically and as a tumor suppressor

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915068107

Mechanism of inhibition of human KSP by ispinesib

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915068107

Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915068107

Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915068107

Pathway of ATP Hydrolysis by Monomeric and Dimeric Kinesin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20167803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0915068107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20167803

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167803%20AND%20SRC:MED&resulttype=core&format=json