(Q30385283)

21 June 2017

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title

Biology of interleukin-22. (English)

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21 June 2017

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Kerstin Wolk

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21 June 2017

Ellen Witte

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21 June 2017

Katrin Witte

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21 June 2017

Katarzyna Warszawska

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21 June 2017

Robert Sabat

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21 June 2017

publication date

2 February 2010

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Seminars in Immunopathology

21 June 2017

published in

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21 June 2017

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21 June 2017

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21 June 2017

page(s)

17-31

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The evaluation of psoriasis therapy with biologics leads to a revision of the current view of the pathogenesis of this disorder

21 June 2017

cites work

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12 December 2020

IL-28, IL-29 and their class II cytokine receptor IL-28R

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12 December 2020

Interleukin 20: discovery, receptor identification, and role in epidermal function

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12 December 2020

Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity

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12 December 2020

Polymorphisms in the interleukin-22 receptor alpha-1 gene are associated with severe chronic rhinosinusitis

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12 December 2020

Comparison of interleukin-22 and interleukin-10 soluble receptor complexes

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12 December 2020

A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist

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12 December 2020

Three decades of psoriasis research: where has it led us?

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12 December 2020

Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts.

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12 December 2020

Hydrodynamic-based delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats

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12 December 2020

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

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12 December 2020

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

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12 December 2020

Murine NKT cells produce Th17 cytokine interleukin-22

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12 December 2020

Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes

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12 December 2020

Plasticity of CD4+ T cell lineage differentiation.

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12 December 2020

Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis

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12 December 2020

Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10.

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12 December 2020

Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis

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12 December 2020

Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells.

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12 December 2020

The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions

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12 December 2020

IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.

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12 December 2020

Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types

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12 December 2020

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

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12 December 2020

Structure of insect-cell-derived IL-22.

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12 December 2020

A novel, soluble homologue of the human IL-10 receptor with preferential expression in placenta

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12 December 2020

Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes

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12 December 2020

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

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12 December 2020

IL-22 increases the innate immunity of tissues

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12 December 2020

IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation

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12 December 2020

Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation

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12 December 2020

Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity

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12 December 2020

Gene expression profiling in autoimmune noninfectious uveitis disease

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12 December 2020

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

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12 December 2020

Common polymorphisms in the interleukin-22 gene are not associated with chronic plaque psoriasis

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12 December 2020

An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment

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12 December 2020

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

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12 December 2020

IL-22 participates in an innate anti-HIV-1 host-resistance network through acute-phase protein induction.

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12 December 2020

Cutting edge: immune cells as sources and targets of the IL-10 family members?

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12 December 2020

Interleukin-10 and the interleukin-10 receptor

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12 December 2020

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

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12 December 2020

IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis

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12 December 2020

Cloning of murine IL-22 receptor alpha 2 and comparison with its human counterpart

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12 December 2020

Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases

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12 December 2020

Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor

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12 December 2020

Interleukin-22: a novel T- and NK-cell derived cytokine that regulates the biology of tissue cells

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12 December 2020

Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma

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12 December 2020

The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells

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12 December 2020

Detailed genetic characterization of the interleukin-23 receptor in psoriasis

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12 December 2020

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

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12 December 2020

Immunopathogenesis of psoriasis

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12 December 2020

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

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12 December 2020

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

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12 December 2020

Interleukin-10 and related cytokines and receptors

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12 December 2020

Is there an interaction between interleukin-10 and interleukin-22?

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12 December 2020

The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation

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12 December 2020

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

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12 December 2020

Inhibition of interleukin-22 attenuates bacterial load and organ failure during acute polymicrobial sepsis

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12 December 2020

IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes

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12 December 2020

Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions

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12 December 2020

Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes

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12 December 2020

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

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12 December 2020

A role for T cell-derived interleukin 22 in psoriatic skin inflammation

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12 December 2020

Memory IL-22-producing CD4+ T cells specific for Candida albicans are present in humans

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12 December 2020

IL-19 and IL-20: two novel cytokines with importance in inflammatory diseases

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12 December 2020

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

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12 December 2020

The melanoma differentiation associated gene mda-7 suppresses cancer cell growth

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12 December 2020

Interleukin-10 and articular cartilage: experimental therapeutical approaches in cartilage disorders.

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12 December 2020

Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R

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12 December 2020

Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism

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12 December 2020

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

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12 December 2020

Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are distinct from classical ILs

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12 December 2020

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

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12 December 2020

Structure of IL-22 bound to its high-affinity IL-22R1 chain

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12 December 2020

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

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12 December 2020

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

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12 December 2020

The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis

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12 December 2020

Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9.

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12 December 2020

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

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12 December 2020

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

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12 December 2020

IL-22-mediated tumor growth reduction correlates with inhibition of ERK1/2 and AKT phosphorylation and induction of cell cycle arrest in the G2-M phase

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12 December 2020

Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

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12 December 2020

Acinar cells of the pancreas are a target of interleukin-22.

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12 December 2020

New activation modus of STAT3: a tyrosine-less region of the interleukin-22 receptor recruits STAT3 by interacting with its coiled-coil domain

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12 December 2020

Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts

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12 December 2020

Identification of Cellular Pathways of "Type 1," Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis

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12 December 2020

Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2

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12 December 2020

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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12 December 2020

Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2

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12 December 2020

Pathogenesis and clinical features of psoriasis

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12 December 2020

Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22

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12 December 2020

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12 December 2020

The role of interleukin-22 in hepatitis C virus infection

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12 December 2020

Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation

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12 December 2020

Cloning and characterization of mouse IL-22 binding protein

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12 December 2020

IL-22R, IL-10R2, and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22.

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12 December 2020

Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)

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12 December 2020

The family of IL-10-related cytokines and their receptors: related, but to what extent?

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12 December 2020

Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17.

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12 December 2020

Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

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12 December 2020

The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

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12 December 2020

Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine

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12 December 2020

IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes

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12 December 2020

Crystal structure of recombinant human interleukin-22

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12 December 2020

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

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12 December 2020

Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22

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12 December 2020

Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes

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12 December 2020

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

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12 December 2020

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not.

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12 December 2020

Evidence for conformationally different states of interleukin-10: binding of a neutralizing antibody enhances accessibility of a hidden epitope.

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12 December 2020

10.1007/S00281-009-0188-X

Identifiers

DOI

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Dimensions Publication ID

21 June 2017

1003877034

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