(Q30376087)

21 June 2017

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title

Protein dynamism and evolvability. (English)

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21 June 2017

Nobuhiko Tokuriki

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21 June 2017

Dan S Tawfik

series ordinal

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21 June 2017

language of work or name

English

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publication date

1 April 2009

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21 June 2017

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inferred from page(s)

published in

Science

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21 June 2017

volume

324

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21 June 2017

issue

5924

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21 June 2017

page(s)

203-207

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A biological cosmos of parallel universes: does protein structural plasticity facilitate evolution?

21 June 2017

cites work

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https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

A hierarchy of timescales in protein dynamics is linked to enzyme catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Allosteric regulation and catalysis emerge via a common route.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Enzyme promiscuity: evolutionary and mechanistic aspects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Antibody multispecificity mediated by conformational diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Thermodynamic fidelity of the mammalian cytochrome P450 2B4 active site in binding substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Molecular evolution of affinity and flexibility in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

How protein stability and new functions trade off

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Atomic resolution structures of CTX-M beta-lactamases: extended spectrum activities from increased mobility and decreased stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Evolution of hormone-receptor complexity by molecular exploitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Evolution of protein fold in the presence of functional constraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Interconversion between two unrelated protein folds in the lymphotactin native state

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Plasticity, evolvability, and modularity in RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

New catalytic structures from an existing ribozyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Continuous molecular evolution of protein-domain structures by single amino acid changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Intrinsically unstructured proteins and their functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Neutralism and selectionism: a network-based reconciliation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Ohno's model revisited: measuring the frequency of potentially adaptive mutations under various mutational drifts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

The relationship between evolutionary and physiological variation in hemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Missense meanderings in sequence space: a biophysical view of protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Modeling evolutionary landscapes: mutational stability, topology, and superfunnels in sequence space

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Evolutionary rate heterogeneity in proteins with long disordered regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Enzyme-like proteins from an unselected library of designed amino acid sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Reconstruction of functional beta-propeller lectins via homo-oligomeric assembly of shorter fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Is there a unifying mechanism for protein folding?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Kinetics and thermodynamics of ligand binding to a molten globular enzyme and its native counterpart

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Evolutionary aspects of protein structure and folding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Evolvability is a selectable trait

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Functional proteins from a random-sequence library

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

Emergence of diverse biochemical activities in evolutionarily conserved structural scaffolds of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1169375

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1169375

1 reference

21 June 2017

1 reference