(Q29812234)

Winged helix-like DNA-binding domain superfamily

1 reference

E2F family

1 reference

E2F-DP heterodimerization region

1 reference

E2F/DP family, winged-helix DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

1 reference

7 November 2018

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

1 reference

7 November 2018

protein binding

4 references

8 April 2019

Functional antagonism between E2F family members

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

transcription factor binding

1 reference

31 January 2018

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

protein heterodimerization activity

1 reference

8 April 2019

Functional antagonism between E2F family members

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

DNA-binding transcription activator activity, RNA polymerase II-specific

DNA-binding transcription repressor activity, RNA polymerase II-specific

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

1 January 2018

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

sequence-specific DNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

cell component

chromatin

1 reference

8 April 2019

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

1 reference

7 November 2018

transcription regulator complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

1 reference

8 April 2019

Rb-E2F complex

1 reference

8 April 2019

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

RNA polymerase II transcription regulator complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

3 references

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

A genome-wide resource for the analysis of protein localisation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

negative regulation of transcription by RNA polymerase II

HDA

biological process

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

1 reference

31 January 2018

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

1 reference

8 April 2019

endomitotic cell cycle

1 reference

8 April 2019

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

imaginal disc development

1 reference

8 April 2019

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

negative regulation of DNA replication

negative regulation of apoptotic process

1 reference

8 April 2019

E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

negative regulation of transcription, DNA-templated

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

p55, the Drosophila ortholog of RbAp46/RbAp48, is required for the repression of dE2F2/RBF-regulated genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

oogenesis

1 reference

8 April 2019

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

negative regulation of G1/S transition of mitotic cell cycle

1 reference

8 April 2019

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

G1/S transition of mitotic cell cycle

1 reference

8 April 2019

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

negative regulation of transcription by RNA polymerase II

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

regulation of cell cycle

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

positive regulation of transcription regulatory region DNA binding

1 reference

8 April 2019

An alternatively spliced form affecting the Marked Box domain of Drosophila E2F1 is required for proper cell cycle regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

E2F/DP family, winged-helix DNA-binding domain

has part(s)

1 reference