(Q29806605)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34707

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Basic leucine zipper domain, Maf-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II transcription regulatory region sequence-specific DNA binding

3 references

1 January 2018

Regulation of synaptic nlg-1/neuroligin abundance by the skn-1/Nrf stress response pathway protects against oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

protein binding

2 references

1 January 2018

The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

Hsp70 protein binding

1 reference

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

GOA

curator

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 reference

1 January 2018

mitochondrion

1 reference

1 January 2018

Mitochondrial SKN-1/Nrf mediates a conserved starvation response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

endoplasmic reticulum

1 reference

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

biological process

cell fate specification

1 reference

1 January 2018

Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

endodermal cell fate specification

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34707&geneProductId=UniProtKB:P34707

1 reference

16 July 2018

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 reference

1 January 2018

regulation of translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 reference

1 January 2018

response to oxidative stress

1 reference

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response

1 reference

1 January 2018

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

determination of adult lifespan

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

Manipulation of behavioral decline in Caenorhabditis elegans with the Rag GTPase raga-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

response to heat

1 reference

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

embryonic pattern specification

1 reference

1 January 2018

Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

positive regulation of gene expression

1 reference

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

mesendoderm development

1 reference

1 January 2018

skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

embryonic digestive tract development

positive regulation of transcription from RNA polymerase II promoter in response to heat stress

1 reference

1 January 2018

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

positive regulation of cellular response to oxidative stress

1 reference

1 January 2018

TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

negative regulation of neuron death

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

2 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

response to paraquat

1 reference

1 January 2018

Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

positive regulation of cellular response to manganese ion

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

2 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

1 January 2018

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34707

Basic-leucine zipper domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34707

Basic leucine zipper domain, Maf-type

1 reference

InterPro Release 71.0