(Q29615592)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

review article

1 reference

title

Pathogen recognition by the innate immune system (English)

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Taro Kawai

1 reference

ORCID Public Data File 2021

author name string

Shizuo Akira

series ordinal

1 reference

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

20 January 2020

language of work or name

1 reference

30 April 2017

publication date

1 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

International Reviews of Immunology

20 January 2020

published in

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

16-34

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

Innate immune recognition

20 January 2020

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Recognition of microorganisms and activation of the immune response

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

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Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

1 May 2017

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The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

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The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

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The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

1 May 2017

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Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

1 May 2017

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The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis

1 May 2017

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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

1 May 2017

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

1 May 2017

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LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

1 May 2017

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Cell type-specific involvement of RIG-I in antiviral response

1 May 2017

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 May 2017

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Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

1 May 2017

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5'-Triphosphate RNA is the ligand for RIG-I

1 May 2017

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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

1 May 2017

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Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

1 May 2017

1 reference

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Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

1 May 2017

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Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

1 May 2017

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

1 May 2017

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 May 2017

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 May 2017

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

1 May 2017

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Peroxisomes are signaling platforms for antiviral innate immunity

1 May 2017

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

1 May 2017

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Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

1 May 2017

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Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

1 May 2017

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

1 May 2017

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

1 May 2017

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RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

1 May 2017

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RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

1 May 2017

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

1 May 2017

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Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

1 May 2017

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NOD-like receptors (NLRs): bona fide intracellular microbial sensors

1 May 2017

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Function of Nod-like receptors in microbial recognition and host defense

1 May 2017

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Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

1 May 2017

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

1 May 2017

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

1 May 2017

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NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

1 May 2017

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NLR family member NLRC5 is a transcriptional regulator of MHC class I genes

1 May 2017

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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

Influenza virus activates inflammasomes via its intracellular M2 ion channel

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

1 May 2017

1 reference

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Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

1 May 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2010.529976

10.3109/08830185.2010.529976

1 May 2017

Identifiers

DOI

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

30 April 2017

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21235323

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21235323%20AND%20SRC:MED&resulttype=core&format=json