(Q28610861)

3 February 2017

title

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis (English)

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3 February 2017

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R. U. Jänicke

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3 February 2017

P. Ng

series ordinal

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3 February 2017

M. L. Sprengart

series ordinal

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3 February 2017

A. G. Porter

series ordinal

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3 February 2017

language of work or name

English

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publication date

19 June 1998

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Journal of Biological Chemistry

3 February 2017

published in

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3 February 2017

volume

273

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3 February 2017

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3 February 2017

page(s)

15540–15545

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Programmed cell death in animal development

3 February 2017

cites work

1 reference

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

21 January 2018

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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

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Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells

21 January 2018

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Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells

21 January 2018

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

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Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis

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Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

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Death substrates come alive

21 January 2018

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Caspases and caspase inhibitors

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

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Nuclear c-Myc plays an important role in the cytotoxicity of tumor necrosis factor alpha in tumor cells

21 January 2018

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ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis

21 January 2018

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ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

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Cyclin D3 sensitizes tumor cells to tumor necrosis factor-induced, c-Myc-dependent apoptosis

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Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

21 January 2018

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

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Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases

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Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

21 January 2018

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Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death.

21 January 2018

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Caspase activity is required for commitment to Fas-mediated apoptosis.

21 January 2018

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Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

21 January 2018

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

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The spectrin membrane skeleton: emerging concepts

21 January 2018

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Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme

21 January 2018

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Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

21 January 2018

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The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

21 January 2018

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Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

21 January 2018

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

1 reference

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Protease inhibitors selectively block T cell receptor-triggered programmed cell death in a murine T cell hybridoma and activated peripheral T cells

21 January 2018

1 reference

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Role of multiple cellular proteases in the execution of programmed cell death.

21 January 2018

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Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

21 January 2018

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Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis

21 January 2018

1 reference

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