(Q28511655)

25 January 2017

title

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1 (English)

1 reference

SOS Ras/Rac guanine nucleotide exchange factor 1

25 January 2017

0 references

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Growth factor receptor bound protein 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

J. Wade

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M. Rozakis-Adcock

1 reference

25 January 2017

R. Fernley

series ordinal

1 reference

25 January 2017

T. Pawson

series ordinal

1 reference

25 January 2017

D. Bowtell

series ordinal

1 reference

25 January 2017

language of work or name

English

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publication date

6 May 1993

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25 January 2017

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25 January 2017

volume

363

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25 January 2017

issue

6424

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25 January 2017

page(s)

83–85

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Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

25 January 2017

cites work

1 reference

7 January 2021

Requirement for c-ras proteins during viral oncogene transformation

1 reference

7 January 2021

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

1 reference

7 January 2021

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1 reference

7 January 2021

Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras

1 reference

7 January 2021

Mechanistic aspects of signaling through Ras in NIH 3T3 cells

1 reference

7 January 2021

Insulin stimulation of gene expression mediated by p21ras activation.

1 reference

7 January 2021

Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities

1 reference

7 January 2021

Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts

1 reference

7 January 2021

Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity

1 reference

7 January 2021

NGF and EGF rapidly activate p21ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation

1 reference

7 January 2021

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1 reference

7 January 2021

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

1 reference

7 January 2021

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

1 reference

7 January 2021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

7 January 2021

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

7 January 2021

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

1 reference

7 January 2021

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

1 reference

7 January 2021

The Son of sevenless Gene Product: a Putative Activator of Ras

1 reference

7 January 2021

The CDC25 protein of Saccharomyces cerevisiae promotes exchange of guanine nucleotides bound to ras.

1 reference

7 January 2021

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

1 reference

7 January 2021

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

1 reference

7 January 2021

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

7 January 2021

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

1 reference

7 January 2021

Solution structure of the SH3 domain of Src and identification of its ligand-binding site

1 reference

7 January 2021

Identification of a ten-amino acid proline-rich SH3 binding site

1 reference

7 January 2021

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1 reference

7 January 2021

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1 reference

7 January 2021

Phosphorylation of the S. cerevisiae Cdc25 in response to glucose results in its dissociation from Ras

1 reference

7 January 2021

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

1 reference

7 January 2021

Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries

1 reference

7 January 2021