(Q28510439)

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Bax involvement in p53-mediated neuronal cell death (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

BCL2-associated X protein

9 November 2019

main subject

1 reference

GOA release 2020-03-11

1 reference

H Xiang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Y Kinoshita

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

C M Knudson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

S J Korsmeyer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

P A Schwartzkroin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

R S Morrison

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 February 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

published in

Journal of Neuroscience

2 references

25 January 2017

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9 November 2019

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

1363-1373

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

9 November 2019

cites work

1 reference

12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

12 December 2020

p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats

1 reference

12 December 2020

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

1 reference

12 December 2020

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

12 December 2020

Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors

1 reference

12 December 2020

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

12 December 2020

Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons

1 reference

12 December 2020

Programmed cell death and the control of cell survival: lessons from the nervous system

1 reference

12 December 2020

Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death

1 reference

12 December 2020

Immunohistochemical evidence for apoptosis in Alzheimerʼs disease

1 reference

12 December 2020

Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

1 reference

12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

12 December 2020

Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia

1 reference

12 December 2020

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

12 December 2020

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

1 reference

12 December 2020

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

12 December 2020

Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

1 reference

12 December 2020

Inhibition of Bax channel-forming activity by Bcl-2

1 reference

12 December 2020

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

12 December 2020

Bax promotes neuronal cell death and is downregulated during the development of the nervous system.

1 reference

12 December 2020

Mitochondrial dysfunction is a primary event in glutamate neurotoxicity

1 reference

12 December 2020

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

12 December 2020

Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

1 reference

12 December 2020

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

1 reference

12 December 2020

ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis

1 reference

12 December 2020

p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons

1 reference

12 December 2020

DNA End Labeling (TUNEL) in Huntington's Disease and Other Neuropathological Conditions

1 reference

12 December 2020

1 reference

12 December 2020

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

1 reference

12 December 2020

p53 protein in sympathetic neurons: cytoplasmic localization and no apparent function in apoptosis

1 reference

12 December 2020

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1 reference

12 December 2020

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

1 reference

12 December 2020

Induction of Neuronal Apoptosis by Excitotoxins Associated with Long‐Lasting Increase of 12‐O‐Tetradecanoylphorbol 13‐Acetate‐Responsive Element‐Binding Activity

1 reference

12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

12 December 2020

p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.

1 reference

12 December 2020

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

1 reference

12 December 2020

1 reference

12 December 2020

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

12 December 2020

Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases

1 reference

12 December 2020

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

12 December 2020

Evidence for apoptotic cell death in Alzheimer's disease.

1 reference

12 December 2020

p53-deficient mice are protected against adrenalectomy-induced apoptosis.

1 reference

12 December 2020

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

1 reference

12 December 2020

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

1 reference

12 December 2020

Bcl-2 overexpression blocks activation of the death protease CPP32/Yama/apopain

1 reference

12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

Evidence for p53-mediated modulation of neuronal viability.

1 reference

12 December 2020

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

12 December 2020

Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

1 reference

12 December 2020

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

1 reference

12 December 2020

The role of free radicals and p53 in neuron apoptosis in vivo

1 reference

12 December 2020

Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus

1 reference

12 December 2020

p53 induction is associated with neuronal damage in the central nervous system

1 reference

12 December 2020

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

1 reference

12 December 2020

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

12 December 2020

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1 reference

12 December 2020

Upregulation of bax protein levels in neurons following cerebral ischemia.

1 reference

12 December 2020

Channel formation by antiapoptotic protein Bcl-2.

1 reference

12 December 2020

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

12 December 2020

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis

1 reference

12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

12 December 2020

Induction of Bax-alpha precedes apoptosis in a human B lymphoma cell line: potential role of the bcl-2 gene family in surface IgM-mediated apoptosis

1 reference

12 December 2020

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

1 reference

12 December 2020

Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins

1 reference

12 December 2020

Checkpoints of dueling dimers foil death wishes

1 reference

12 December 2020

p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells

1 reference

12 December 2020

Apoptosis in the pathogenesis and treatment of disease

1 reference

12 December 2020

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

1 reference

12 December 2020

DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures.

1 reference

12 December 2020

Multiple molecular weight forms of basic fibroblast growth factor are developmentally regulated in the central nervous system

1 reference

12 December 2020

Growth factor modulation of p53-mediated growth arrest versus apoptosis

1 reference

12 December 2020

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1 reference

12 December 2020

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

12 December 2020

Tetrazolium salts and formazans

1 reference

12 December 2020

Rapid allelotype analysis of p53 knockout mice

1 reference

12 December 2020

Bcl-2 and Bax function independently to regulate cell death

1 reference

12 December 2020

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

1 reference

12 December 2020

Mitochondrial permeability transition is a central coordinating event of apoptosis

1 reference

12 December 2020

Generation and identification of recombinant adenovirus by liposome-mediated transfection and PCR analysis.

1 reference

12 December 2020

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

1 reference

12 December 2020

STUDIES ON SUCCINATE-TETRAZOLIUM REDUCTASE SYSTEMS. III. POINTS OF COUPLING OF FOUR DIFFERENT TETRAZOLIUM SALTS

1 reference

12 December 2020

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

12 December 2020

Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

1 reference

12 December 2020

Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

1 reference

12 December 2020

Wild-type p53 activates transcription in vitro

1 reference

12 December 2020

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

1 reference

12 December 2020

Identification of p53 as a sequence-specific DNA-binding protein

1 reference

12 December 2020

Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

1 reference

12 December 2020

p53 expression in brain after middle cerebral artery occlusion in the rat

1 reference

12 December 2020

Double identity for proteins of the Bcl-2 family

1 reference

12 December 2020

10.1523/JNEUROSCI.18-04-01363.1998

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9454845%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

2 references

25 January 2017

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