(Q28505083)

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions (English)

2 references

PubMed

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

Ligase IV, DNA, ATP-dependent

5 December 2019

main subject

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

D O Ferguson

1 reference

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5 December 2019

R C O'Hagan

1 reference

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5 December 2019

D H Castrillon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

C Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

P A Farazi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

S Alson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

J Fleming

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

C C Morton

1 reference

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5 December 2019

K Frank

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

L Chin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

F W Alt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

R A DePinho

1 reference

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5 December 2019

publication date

1 December 2001

2 references

PubMed

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

page(s)

1187-1196

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

5 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

The interplay between nonhomologous end-joining and cell cycle checkpoint factors in development, genomic stability, and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Tumour-suppressor genes: evolving definitions in the genomic age

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Loss of heterozygosity and lack of mutations of the XPG/ERCC5 DNA repair gene at 13q33 in prostate cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

DNA copy number losses in human neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Identification of recurrent chromosomal rearrangements and the unique relationship between low-level amplification and translocation in glioblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Limitations of chromosome classification by multicolor karyotyping

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Analysis of ku80-mutant mice and cells with deficient levels of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Multicolour spectral karyotyping of mouse chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Cytogenetic analysis in the examination of solid tumors in children

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Characterization of the 12q13-15 amplicon in soft tissue tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Hypersensitivity ofKu80-deficient cell lines and mice to DNA damage: The effects of ionizing radiation on growth, survival, and development

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Frequent chromosomal translocations induced by DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

p53-independent role of MDM2 in TGF-beta1 resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Ku86 variant expression and function in multiple myeloma cells is associated with increased sensitivity to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

DNA amplification and chromosomal translocations are accompanied by chromosomal instability: analysis of seven human colon cancer cell lines by comparative genomic hybridization and spectral karyotyping

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

MDM-2 oncoprotein overexpression, p53 gene mutation, and VEGF up-regulation in angiosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900425-7

7 January 2021

10.1016/S1097-2765(01)00425-7

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json