(Q28597156)

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Human Germline Mutation and the Erratic Evolutionary Clock

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Human Germline Mutation and the Erratic Evolutionary Clock (English)

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Molly Przeworski

3

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Priya Moorjani

1

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Ziyue Gao

2

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publication date

October 2016

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14

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10

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e2000744

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Creative Commons Attribution 4.0 International

19 October 2016

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April 2022 Public Data File from Crossref

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Variation in the molecular clock of primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Analysis of protein-coding genetic variation in 60,706 humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Direct estimate of the rate of germline mutation in a bird

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Mutation rates and the evolution of germline structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Inferences from tip-calibrated phylogenies: a review and a practical guide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Life history effects on the molecular clock of autosomes and sex chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Post-zygotic Point Mutations Are an Underrecognized Source of De Novo Genomic Variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Genome sequence of a 45,000-year-old modern human from western Siberia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Mutational signatures: the patterns of somatic mutations hidden in cancer genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Properties and rates of germline mutations in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Estimating the human mutation rate using autozygosity in a founder population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Rate of de novo mutations and the importance of father's age to disease risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Insights into hominid evolution from the gorilla genome sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Variation in genome-wide mutation rates within and between human families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

A molecular phylogeny of living primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Evolution of the mutation rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Analysis of genetic inheritance in a family quartet by whole-genome sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Biased gene conversion and the evolution of mammalian genomic landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Age and sex effects on human mutation rates: an old problem with new complexities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Genetic evidence for complex speciation of humans and chimpanzees

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Molecular clocks: four decades of evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Initial sequence of the chimpanzee genome and comparison with the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

The rate of DNA evolution: effects of body size and temperature on the molecular clock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Genomic data support the hominoid slowdown and an Early Oligocene estimate for the hominoid-cercopithecoid divergence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

The modern molecular clock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Estimating ancestral population sizes and divergence times

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

The origins, patterns and implications of human spontaneous mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

dbSNP: the NCBI database of genetic variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Estimate of the mutation rate per nucleotide in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Quality control by DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Spontaneous mutation and parental age in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

The molecular clock runs more slowly in man than in apes and monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

17 March 2017

Cross-cultural estimation of the human generation interval for use in genetics-based population divergence studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

7 April 2017

Primate molecular divergence dates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

7 April 2017

Mutation rates in mammalian genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

7 April 2017

Evidence for higher rates of nucleotide substitution in rodents than in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

7 April 2017

Rates of DNA sequence evolution differ between taxonomic groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

7 April 2017

DO VARIATIONS IN SUBSTITUTION RATES AND MALE MUTATION BIAS CORRELATE WITH LIFE-HISTORY TRAITS? A STUDY OF 32 MAMMALIAN GENOMES

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

9 May 2017

The mutation rate in human evolution and demographic inference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Parent-of-origin-specific signatures of de novo mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Physical and neurobehavioral determinants of reproductive onset and success

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Germline Stem Cell Competition, Mutation Hot Spots, Genetic Disorders, and Older Fathers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

New observations on maternal age effect on germline de novo mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Interpreting the Dependence of Mutation Rates on Age and Time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Timing, rates and spectra of human germline mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

The origins, determinants, and consequences of human mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Genome-wide patterns and properties of de novo mutations in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

The genome-wide effects of ionizing radiation on mutation induction in the mammalian germline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Evidence for recent, population-specific evolution of the human mutation rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Generation time, life history and the substitution rate of neutral mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Lineage sorting in apes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Determinants of mutation rate variation in the human germline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Whole-genome sequence variation, population structure and demographic history of the Dutch population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Toward better understanding of artifacts in variant calling from high-coverage samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Nonhuman genetics. Strong male bias drives germline mutation in chimpanzees

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Cellular evidence for selfish spermatogonial selection in aged human testes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Great ape genetic diversity and population history

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Whole-genome sequencing in autism identifies hot spots for de novo germline mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Evidence for elevated mutation rates in low-quality genotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Whole genome sequencing for quantifying germline mutation frequency in humans and model species: cautious optimism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Time-dependent rates of molecular evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Genotype and SNP calling from next-generation sequencing data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Measurements of spontaneous rates of mutations in the recent past and the near future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Sperm competition and sperm length influence the rate of mammalian spermatogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Bayesian Markov chain Monte Carlo sequence analysis reveals varying neutral substitution patterns in mammalian evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

The comparative demography of primates: with some comments on the evolution of life histories

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Biological basis of germline mutation: comparisons of spontaneous germline mutation rates among drosophila, mouse, and human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

The temperature influence on the spontaneous mutation rate. I. Literature review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Effects of linkage on rates of molecular evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

29 September 2017

Whole-genome sequencing of quartet families with autism spectrum disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

3 June 2018

Inferring human population size and separation history from multiple genome sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

3 June 2018

Revising the human mutation rate: implications for understanding human evolution

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

Dates from the molecular clock: how wrong can we be?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

Genome sequencing of normal cells reveals developmental lineages and mutational processes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

The rate of spontaneous mutation of a human gene

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

Rate of Fixation of Nucleotide Substitutions in Evolution

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

Strong variations of mitochondrial mutation rate across mammals--the longevity hypothesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

The human mutation rate is increasing, even as it slows

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

DNA repair efficiency and thermotolerance in Drosophila melanogaster from "Evolution Canyon".

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2000744

21 January 2018

The role of immunochemical differences in the phyletic development of human behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070741

27 November 2018

Slow molecular clocks in Old World monkeys, apes, and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27760127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of the immunologic species specificity of human serum proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/27760127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rate of spontaneous mutation of a human gene. 1935.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27760127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germline and somatic mosaicism in a female carrier of Duchenne muscular dystrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/27760127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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