(Q28586410)

31 January 2017

title

Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells (English)

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Rac family small GTPase 2

31 January 2017

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GOA release 2020-03-11

F. C. Yang

1 reference

31 January 2017

R. Kapur

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31 January 2017

A. J. King

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31 January 2017

W. Tao

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31 January 2017

C. Kim

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31 January 2017

J. Borneo

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31 January 2017

R. Breese

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31 January 2017

M. Marshall

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31 January 2017

M. C. Dinauer

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31 January 2017

D. A. Williams

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31 January 2017

language of work or name

English

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publication date

1 May 2000

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

557–568

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Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

31 January 2017

cites work

1 reference

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7 January 2021

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

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7 January 2021

Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils

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7 January 2021

Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

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7 January 2021

Gelsolin is a downstream effector of rac for fibroblast motility

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7 January 2021

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

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7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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7 January 2021

Crosstalk between Rac and Rho.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Interferon-gamma inhibits serotonin release from mouse peritoneal mast cells

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7 January 2021

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

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7 January 2021

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

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7 January 2021

Rac GTPase interacts with GAPs and target proteins through multiple effector sites.

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7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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7 January 2021

The two faces of the mast cell

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7 January 2021

Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis.

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7 January 2021

Characterization of RAC3, a novel member of the Rho family

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7 January 2021

Rho GTPases and the actin cytoskeleton

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7 January 2021

IgE antibody up-regulates high affinity IgE binding on murine bone marrow-derived mast cells

1 reference

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7 January 2021

A Rac1 effector site controlling mitogenesis through superoxide production

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7 January 2021

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

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7 January 2021

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

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7 January 2021

Membrane association of Rac is required for high activity of the respiratory burst oxidase

1 reference

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7 January 2021

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

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7 January 2021

Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Pheromone signalling and polarized morphogenesis in yeast

1 reference

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7 January 2021

Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

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7 January 2021

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

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7 January 2021

A safe packaging line for gene transfer: separating viral genes on two different plasmids

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7 January 2021

Bad can act as a key regulator of T cell apoptosis and T cell development.

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7 January 2021

Clonal origin of murine hemopoietic colonies with apparent restriction to granuclocyte-macrophage-megakaryocyte (GMM) differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Anti-apoptotic function of Rac in hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Purification and identification of FOAD-II, a cytosolic protein that regulates secretion in streptolysin-O permeabilized mast cells, as a rac/rhoGDI complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

An essential role for Rac in Ras transformation

1 reference

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7 January 2021

A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation

1 reference

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7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

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7 January 2021

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Inhibition of myosin light chain kinase by p21-activated kinase

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1 reference

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7 January 2021

Rho GTPases and signaling networks

1 reference

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7 January 2021

VLA-5 is expressed by mouse and human long-term repopulating hematopoietic cells and mediates adhesion to extracellular matrix protein fibronectin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Rho family members: Activators of MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Increasing complexity of the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

c-kit receptor signaling through its phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Signaling functions of L-selectin. Enhancement of tyrosine phosphorylation and activation of MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Multiple Ras functions can contribute to mammalian cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Interleukin-11 mRNA stabilization in phorbol ester-stimulated primate bone marrow stromal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980207-1

7 January 2021

10.1016/S1074-7613(00)80207-1

Identifiers

DOI

0 references

1 reference