(Q28586447)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

Cytochrome b-245, alpha polypeptide

7 February 2020

main subject

1 reference

GOA release 2020-03-11

SH3 and PX domains 2A

1 reference

GOA release 2020-03-11

reactive oxygen species

1 reference

0 references

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Gidon Shani

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Ian Pass

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Diana Anderson

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Manuela Quintavalle

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Sara A Courtneidge

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

15 September 2009

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

ra53

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

7 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2810640/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation

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A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo

17 March 2017

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Assembly and biological role of podosomes and invadopodia

17 March 2017

1 reference

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The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

17 March 2017

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CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery

17 March 2017

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17 March 2017

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Invadopodia: specialized cell structures for cancer invasion

17 March 2017

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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

17 March 2017

1 reference

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Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

17 March 2017

1 reference

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Molecular basis of phosphorylation-induced activation of the NADPH oxidase

17 March 2017

1 reference

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The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells

17 March 2017

1 reference

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Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis

17 March 2017

1 reference

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Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton

17 March 2017

1 reference

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Phosphatidylinositol 3,4,5-trisphosphate directs association of Src homology 2-containing signaling proteins with gelsolin

17 March 2017

1 reference

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Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5

17 March 2017

1 reference

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Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

17 March 2017

1 reference

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A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate

17 March 2017

1 reference

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NOX enzymes and the biology of reactive oxygen

17 March 2017

1 reference

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Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

7 April 2017

1 reference

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EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2.

7 April 2017

1 reference

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The role of mitochondria in reactive oxygen species metabolism and signaling

29 September 2017

1 reference

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Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts

29 September 2017

1 reference

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The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function

29 September 2017

1 reference

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Sequential signals toward podosome formation in NIH-src cells.

29 September 2017

1 reference

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Regulation of ROS signal transduction by NADPH oxidase 4 localization

29 September 2017

1 reference

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Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.

29 September 2017

1 reference

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Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis

29 September 2017

1 reference

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Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

29 September 2017

1 reference

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Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras.

29 September 2017

1 reference

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Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species

29 September 2017

1 reference

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Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes

29 September 2017

1 reference

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Chronic inflammation and oxidative stress in human carcinogenesis

29 September 2017

1 reference

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ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging

29 September 2017

1 reference

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Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes

29 September 2017

1 reference

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Regulation of Nox and Duox enzymatic activity and expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The signaling mechanism of ROS in tumor progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The SRC substrate Tks5, podosomes (invadopodia), and cancer cell invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Oxidative and nitrative DNA damage as biomarker for carcinogenesis with special reference to inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Structure and dynamics of macrophage podosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Subcellular targeting of oxidants during endothelial cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Redox redux: revisiting PTPs and the control of cell signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

29 September 2017

Podosomes at a glance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Role of synaptojanin 2 in glioma cell migration and invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Increased Nox1 and hydrogen peroxide in prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Active Rho is localized to podosomes induced by oncogenic Src and is required for their assembly and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

NADPH oxidases: not just for leukocytes anymore!

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Oxidant signals and oxidative stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

An NAD(P)H oxidase regulates growth and transcription in melanoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The neutrophil NADPH oxidase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Specialized surface protrusions of invasive cells, invadopodia and lamellipodia, have differential MT1-MMP, MMP-2, and TIMP-2 localization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Proteolysis of extracellular matrix by invadopodia facilitates human breast cancer cell invasion and is mediated by matrix metalloproteinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

Overexpression of a novel superoxide-producing enzyme, NADPH oxidase 1, in adenoma and well differentiated adenocarcinoma of the human colon

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

PTP-PEST controls motility through regulation of Rac1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810640

A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells

27 November 2018

1 reference

12 December 2020

Endogenous reactive oxygen intermediates activate tyrosine kinases in human neutrophils

1 reference

12 December 2020

NADPH oxidase activity is required for endothelial cell proliferation and migration

1 reference

12 December 2020

Phagocytosis of cross-linked gelatin matrix by human breast carcinoma cells correlates with their invasive capacity

1 reference

12 December 2020

PYK2 is an adhesion kinase in macrophages, localized in podosomes and activated by beta(2)-integrin ligation

1 reference

12 December 2020

Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS)

1 reference

12 December 2020

10.1126/SCISIGNAL.2000368

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19755709%20AND%20SRC:MED&resulttype=core&format=json