(Q28584353)

English

X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1)

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PubMed publication ID

31 January 2017

X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1) (English)

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PubMed publication ID

31 January 2017

apoptotic process

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author name string

Swayamjot Kaur

1

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PubMed publication ID

31 January 2017

Fang Wang

2

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PubMed publication ID

31 January 2017

Manickam Venkatraman

3

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PubMed publication ID

31 January 2017

Marcello Arsura

4

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PubMed publication ID

31 January 2017

language of work or name

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publication date

18 November 2005

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PubMed publication ID

31 January 2017

Journal of Biological Chemistry

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PubMed publication ID

31 January 2017

280

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PubMed publication ID

31 January 2017

46

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PubMed publication ID

31 January 2017

38599–38608

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PubMed publication ID

31 January 2017

TGF-beta in liver development, regeneration, and carcinogenesis

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Transcriptional control by the TGF-beta/Smad signaling system

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Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells

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To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions

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XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

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Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus.

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Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

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ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage

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TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha

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Inhibition of JNK activation through NF-kappaB target genes

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Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

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Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

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Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement.

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X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes

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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

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TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

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TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development

1 reference

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Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drosophila

1 reference

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Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

1 reference

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The role of multiubiquitination in dislocation and degradation of the alpha subunit of the T cell antigen receptor

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NF-kappaB at the crossroads of life and death

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Role of JNK activation in apoptosis: a double-edged sword

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Characterization of XIAP-deficient mice

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Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

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Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation

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X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling

1 reference

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IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

1 reference

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ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis

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1 reference

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TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

1 reference

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Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis

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Functions of c-Jun in liver and heart development

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Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation

1 reference

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

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Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells

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Identifiers

10.1074/JBC.M505671200

1 reference

PubMed publication ID

31 January 2017

PubMed publication ID

1 reference

PubMed publication ID

31 January 2017

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