(Q28584039)

31 January 2017

title

JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells (English)

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31 January 2017

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Ohn Soon Kim

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31 January 2017

Eun Jung Park

series ordinal

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31 January 2017

Eun-hye Joe

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31 January 2017

Ilo Jou

series ordinal

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31 January 2017

language of work or name

English

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publication date

25 October 2002

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

277

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31 January 2017

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31 January 2017

page(s)

40594–40601

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Gangliosides in isolated neurons and glial cells.

31 January 2017

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Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains

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Structural transitions associated with the interaction of Alzheimer beta-amyloid peptides with gangliosides.

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Reduction in cholesterol and sialic acid content protects cells from the toxic effects of beta-amyloid peptides

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Gangliosides GD1b, GT1b, and GQ1b enhance IL-2 and IFN-gamma production and suppress IL-4 and IL-5 production in phytohemagglutinin-stimulated human T cells

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Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression

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Protein-DNA interactions in interferon-gamma signaling

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

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21 January 2018

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Brain dendritic cells and macrophages/microglia in central nervous system inflammation

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Interleukin-13 and -4 induce death of activated microglia

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An essential role of the JAK-STAT pathway in ischemic preconditioning

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DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites

21 January 2018

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Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation

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Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling

21 January 2018

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Gangliosides GM1 and GM2 induce vascular smooth muscle cell proliferation via extracellular signal-regulated kinase 1/2 pathway

21 January 2018

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Successive isolation and separation of the major lipid fractions including gangliosides from single biological samples

21 January 2018

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Direct evidence that ganglioside is an integral component of the thyrotropin receptor

21 January 2018

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Association of Src family tyrosine kinase Lyn with ganglioside GD3 in rat brain. Possible regulation of Lyn by glycosphingolipid in caveolae-like domains.

21 January 2018

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ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains

21 January 2018

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STATs and gene regulation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Interleukin-11 induces complex formation of Grb2, Fyn, and JAK2 in 3T3L1 cells

21 January 2018

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Macrophages and inflammatory mediators in tissue injury

21 January 2018

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Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture

21 January 2018

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Overexpression of ganglioside GM1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals

21 January 2018

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Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation

21 January 2018

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Lipid rafts and signal transduction

21 January 2018

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GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells

21 January 2018

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Jak-STAT signaling induced by the v-abl oncogene

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M203885200

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31 January 2017

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