(Q28576942)

31 January 2017

title

Leptin plays a catabolic role on articular cartilage (English)

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31 January 2017

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Jia-peng Bao

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31 January 2017

Wei-ping Chen

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31 January 2017

Jie Feng

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31 January 2017

Peng-fei Hu

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31 January 2017

Zhong-li Shi

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31 January 2017

Li-dong Wu

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31 January 2017

publication date

1 October 2010

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Molecular Biology Reports

31 January 2017

published in

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

3265–3272

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The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

31 January 2017

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Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis

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Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

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Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage

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Aggrecan degradation in human intervertebral disc and articular cartilage

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The role of proteases in the pathogenesis of osteoarthritis

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12 December 2020

Degradation of type II collagen, but not proteoglycan, correlates with matrix metalloproteinase activity in cartilage explant cultures

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12 December 2020

Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

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12 December 2020

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

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12 December 2020

Positional cloning of the mouse obese gene and its human homologue

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The splice variants VEGF121 and VEGF189 of the angiogenic peptide vascular endothelial growth factor are expressed in osteoarthritic cartilage

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Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis

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12 December 2020

Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity

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12 December 2020

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12 December 2020

Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes

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12 December 2020

Unraveling the central nervous system pathways underlying responses to leptin

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12 December 2020

Evidence for a key role of leptin in osteoarthritis

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12 December 2020

Cartilage proteoglycan alterations in an experimentally induced model of rabbit osteoarthritis

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12 December 2020

Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes

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12 December 2020

Fibroblast growth factor stimulates colony formation of differentiated chondrocytes in soft agar.

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12 December 2020

Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor

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12 December 2020

Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling

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12 December 2020

The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation

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12 December 2020

A critical role for collagen II in cartilage matrix degradation: collagen II induces pro-inflammatory cytokines and MMPs in primary human chondrocytes

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12 December 2020

Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips

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12 December 2020

Aggrecanases and aggrecanase-generated fragments in the human intervertebral disc at early and advanced stages of disc degeneration

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Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

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ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage

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12 December 2020

Role of leptin in the neuroendocrine response to fasting

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12 December 2020

Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair

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Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage

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12 December 2020

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

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Development and regulation of osteophyte formation during experimental osteoarthritis

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Expression changes of gelatinases in human osteoarthritic knees and arthroscopic debridement

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12 December 2020

Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections

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12 December 2020

Effect of transforming growth factor-beta and platelet-derived growth factor-BB on articular cartilage in rats

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12 December 2020

Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose

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12 December 2020

Fibroblast growth factor-2 promotes the repair of partial thickness defects of articular cartilage in immature rabbits but not in mature rabbits

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12 December 2020

Leptin is a potent stimulator of bone growth in ob/ob mice

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12 December 2020

Basic fibroblast growth factor activates the MAPK and NFkappaB pathways that converge on Elk-1 to control production of matrix metalloproteinase-13 by human adult articular chondrocytes

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12 December 2020

Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization

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12 December 2020

Vascular endothelial growth factor in articular cartilage of healthy and osteoarthritic human knee joints.

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12 December 2020

An introduction to the pathophysiology of osteoarthritis

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12 December 2020

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

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12 December 2020

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12 December 2020

Mechanism of catabolism of aggrecan by articular cartilage

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12 December 2020

Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism

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12 December 2020

The relative importance of cysteine peptidases in osteoarthritis

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12 December 2020

The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B

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12 December 2020

Leptin consumption in the inflamed joints of patients with rheumatoid arthritis

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12 December 2020

The therapeutic effects of basic fibroblast growth factor contained in gelatin hydrogel microspheres on experimental osteoarthritis in the rabbit knee

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12 December 2020

The osteoblast: a sophisticated fibroblast under central surveillance

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12 December 2020

Proteoglycans: many forms and many functions

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12 December 2020

Beneficial effect of basic fibroblast growth factor on the repair of full-thickness defects in rabbit articular cartilage

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12 December 2020

Identification and expression cloning of a leptin receptor, OB-R

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12 December 2020

Quantitative criteria for evaluating the early development of osteoarthritis and the effect of diclofenac sodium

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12 December 2020

Synergistic induction of nitric oxide synthase type II: in vitro effect of leptin and interferon-gamma in human chondrocytes and ATDC5 chondrogenic cells

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12 December 2020

Raised serum vascular endothelial growth factor levels are associated with destructive change in inflammatory arthritis

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12 December 2020