(Q28570052)

31 January 2017

title

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide (English)

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31 January 2017

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Erich Gulbins

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Dieter Häussinger

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31 January 2017

Herbert Rübben

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31 January 2017

Philipp A. Lang

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31 January 2017

Marcus Schenck

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31 January 2017

Jan P. Nicolay

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31 January 2017

Jan Ulrich Becker

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31 January 2017

Daniela S. Kempe

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31 January 2017

Adrian Lupescu

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31 January 2017

Saisudha Koka

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31 January 2017

Kerstin Eisele

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31 January 2017

Barbara A. Klarl

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31 January 2017

Kurt W. Schmid

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31 January 2017

Klaus Mann

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31 January 2017

Sibylle Hildenbrand

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31 January 2017

Harald Hefter

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31 January 2017

Stephan M. Huber

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31 January 2017

Thomas Wieder

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31 January 2017

Andreas Erhardt

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31 January 2017

Florian Lang

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31 January 2017

language of work or name

English

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publication date

1 February 2007

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

164–170

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hCTR1: a human gene for copper uptake identified by complementation in yeast

31 January 2017

cites work

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7 January 2021

Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. Monoclonal antibody production, isolation, and localization

1 reference

7 January 2021

The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity

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7 January 2021

The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene

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7 January 2021

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

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7 January 2021

Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease

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7 January 2021

Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase

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7 January 2021

Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases

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7 January 2021

Biochemical characterization of the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae

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7 January 2021

Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion

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7 January 2021

PROGRESSIVE LENTICULAR DEGENERATION: A FAMILIAL NERVOUS DISEASE ASSOCIATED WITH CIRRHOSIS OF THE LIVER

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7 January 2021

The copper and iron content of brain and liver in the normal and in hepato-lenticular degeneration

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7 January 2021

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7 January 2021

In vitro assessment of copper-induced toxicity in the human hepatoma line, Hep G2.

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7 January 2021

Oxidative stress, mitochondrial permeability transition, and cell death in Cu-exposed trout hepatocytes.

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7 January 2021

Lysosomal involvement in hepatocyte cytotoxicity induced by Cu(2+) but not Cd(2+).

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7 January 2021

Hemolytic Anemia in Wilson's Disease

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7 January 2021

Hemolytic anemia in wilson disease: Clinical findings and biochemical mechanisms

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7 January 2021

CD95 Signaling via Ceramide-rich Membrane Rafts

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7 January 2021

Ceramide enables fas to cap and kill.

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7 January 2021

TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis

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7 January 2021

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

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7 January 2021

Caspase-dependent and -independent activation of acid sphingomyelinase signaling

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7 January 2021

Acid sphingomyelinase is indispensable for UV light-induced Bax conformational change at the mitochondrial membrane.

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7 January 2021

Reactive oxygen species limit neutrophil life span by activating death receptor signaling

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7 January 2021

Bile salt-induced apoptosis involves NADPH oxidase isoform activation

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7 January 2021

Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts

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7 January 2021

Sindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide

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7 January 2021

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

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7 January 2021

Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes

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7 January 2021

Activation of human acid sphingomyelinase through modification or deletion of C-terminal cysteine

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7 January 2021

The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts

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7 January 2021

The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene

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7 January 2021

Apoptosis: the importance of being eaten

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7 January 2021

A receptor for phosphatidylserine-specific clearance of apoptotic cells

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7 January 2021

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

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7 January 2021

The nature of piecemeal necrosis in chronic active hepatitis

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7 January 2021

ICE inhibitor YVADcmk is a potent therapeutic agent against in vivo liver apoptosis

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7 January 2021

Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes.

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7 January 2021

PGE(2) in the regulation of programmed erythrocyte death

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7 January 2021