(Q28306715)

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Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1

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Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1 (English)

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1 reference

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author name string

Wen Liu

1

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Yi-Juan Huang

2

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Cong Liu

3

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Yan-Yong Yang

4

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Hu Liu

5

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Jian-Guo Cui

6

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Ying Cheng

7

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Fu Gao

8

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Jian-Ming Cai

9

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Bai-Long Li

10

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language of work or name

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publication date

April 2014

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Laboratory Investigation

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94

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4

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362-70

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Global cancer statistics

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

Cancer statistics, 2008

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

The basics of epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding [...]

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2013.153

20 April 2017

Dissemination and growth of cancer cells in metastatic sites

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

20 April 2017

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

20 April 2017

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

20 April 2017

Lung cancer in China: challenges and interventions

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Definitive chemoradiation for the treatment of locally advanced non small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

New radiotherapy and chemoradiotherapy approaches for non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Radiation and the microenvironment - tumorigenesis and therapy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

A sense of danger from radiation.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Treatment of limited small cell lung cancer: an old or new challenge?

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Treatment of brain metastasis from lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Metastasis: recent discoveries and novel treatment strategies

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Ionizing radiation promotes migration and invasion of cancer cells through transforming growth factor-beta-mediated epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

miR-200c enhances radiosensitivity of human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Inhibition of glycogen synthase kinase 3 beta attenuates neurocognitive dysfunction resulting from cranial irradiation.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Glycogen synthase kinase 3β inhibitors protect hippocampal neurons from radiation-induced apoptosis by regulating MDM2-p53 pathway

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Prediction of radiation pneumonitis in lung cancer patients: a systematic review.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Glycogen synthase kinase-3 (GSK-3) regulates TGF-β₁-induced differentiation of pulmonary fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

RalB signaling: a bridge between inflammation and cancer

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

Role of Radiation-induced TGF-beta Signaling in Cancer Therapy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

The hepatitis B viral X protein activates NF-kappaB signaling pathway through the up-regulation of TBK1.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.153

21 January 2018

The miR-200 family regulates TGF-β1-induced renal tubular epithelial to mesenchymal transition through Smad pathway by targeting ZEB1 and ZEB2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does ionizing radiation stimulate cancer invasion and metastasis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiation induces epithelial-mesenchymal transition in colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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