(Q28362294)

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E G Roe

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B C Jones

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D A Smith

British Journal of Clinical Pharmacology

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language of work or name

English

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publication date

March 2001

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published in

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volume

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issue

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page(s)

239-48

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cites work

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In vitro biotransformation of sildenafil (Viagra): identification of human cytochromes and potential drug interactions

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Isolation and characterization of a cytochrome P450 of the IIA subfamily from human liver microsomes

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

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Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir

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Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo data.

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Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

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Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine

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Characterization of the selectivity and mechanism of human cytochrome P450 inhibition by the human immunodeficiency virus-protease inhibitor nelfinavir mesylate

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Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

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Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction

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Midazolam alpha-hydroxylation by human liver microsomes in vitro: inhibition by calcium channel blockers, itraconazole and ketoconazole

21 January 2018

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Interaction of sildenafil and indinavir when co-administered to HIV-positive patients

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12 December 2020

Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography

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Oxidation of quinidine by human liver cytochrome P-450

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High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

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Purification and characterization of liver microsomal cytochrome P-450 from untreated male rats

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Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes

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Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

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Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

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Sildenafil, a novel effective oral therapy for male erectile dysfunction

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Identification of human cytochrome P450 isoforms involved in the metabolism of brotizolam

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Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6

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Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man

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12 December 2020

10.1046/J.1365-2125.2001.00318.X

Identifiers

DOI

1 reference

1 reference

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PubMed publication ID

11298070

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