(Q28344005)

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T Gatbonton

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W P Irvine

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D E Gottschling

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J A Simon

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

18 December 2001

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published in

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volume

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issue

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page(s)

15113-8

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cites work

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Negative control of p53 by Sir2alpha promotes cell survival under stress

20 March 2017

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Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

20 March 2017

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Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association

20 March 2017

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Structure of the histone deacetylase SIRT2

20 March 2017

1 reference

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Crystal structure of a SIR2 homolog-NAD complex

20 March 2017

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A novel form of transcriptional silencing by Sum1-1 requires Hst1 and the origin recognition complex

20 March 2017

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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

20 March 2017

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Deacetylation of p53 modulates its effect on cell growth and apoptosis

20 March 2017

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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

20 March 2017

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A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

20 March 2017

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The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

20 March 2017

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

20 March 2017

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Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae

20 March 2017

1 reference

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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

20 March 2017

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Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity

20 March 2017

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Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae

20 March 2017

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Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

20 March 2017

1 reference

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A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

20 March 2017

1 reference

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Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

20 March 2017

1 reference

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Extrachromosomal rDNA circles--a cause of aging in yeast

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

An unusual form of transcriptional silencing in yeast ribosomal DNA

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Chromatin remodeling: why it is important in cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Conversion of a gene-specific repressor to a regional silencer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Enzymatic activities of Sir2 and chromatin silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

25 years after the nucleosome model: chromatin modifications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Yeast heterochromatin is a dynamic structure that requires silencers continuously

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Epigenetics and its role in disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Regulation of E2F1 activity by acetylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

X-chromosome inactivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Silencing and heritable domains of gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Cell cycle arrest caused by CLN gene deficiency in Saccharomyces cerevisiae resembles START-I arrest and is independent of the mating-pheromone signalling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Signal transduction during pheromone response in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Global histone acetylation and deacetylation in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64992

DNA replication-independent silencing in S. cerevisiae.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.261574398

Role of DNA replication in the repression of silent mating type loci in yeast

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.261574398

Silencers are required for inheritance of the repressed state in yeast.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.261574398

Establishment of transcriptional silencing in the absence of DNA replication

21 January 2018

1 reference

12 December 2020

Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast

1 reference

12 December 2020

Silenced chromatin is permissive to activator binding and PIC recruitment

1 reference

12 December 2020

Acetylation control of the retinoblastoma tumour-suppressor protein

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.261574398

1 reference

release_vsoegwqjbfg2rg4jatqkkxh63q

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1374381

1 reference

1 reference

1374381

PubMed publication ID

11752457

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